Journal ArticleDOI
Novel biodegradable polyphosphate cross-linker for making biocompatible hydrogel.
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TLDR
PIOP is a hydrolyzable polymer, which can be used as a cross-linker, and novel hydrogels having biodegradability and biocompatibility were prepared from poly(MPC) cross-linked with the PIOP.About:
This article is published in Biomacromolecules.The article was published on 2004-04-09. It has received 47 citations till now. The article focuses on the topics: Self-healing hydrogels & Radical polymerization.read more
Citations
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Journal ArticleDOI
Poly(phosphoester)s: A New Platform for Degradable Polymers
TL;DR: Recent studies have illustrated the potential of PPEs for future applications beyond flame retardancy, and provided a coherent vision to implement this classic biopolymer in modern applications that demand biocompatibility and degradability as well as the possibility to adjust the properties to individual needs.
Journal ArticleDOI
Rapid and Versatile Construction of Diverse and Functional Nanostructures Derived from a Polyphosphoester-Based Biomimetic Block Copolymer System
Shiyi Zhang,Jiong Zou,Fuwu Zhang,Mahmoud Elsabahy,Mahmoud Elsabahy,Simcha E. Felder,Jiahua Zhu,Darrin J. Pochan,Karen L. Wooley +8 more
TL;DR: This paper demonstrates the rapid and facile preparation of a family of nanoparticles with different surface charges and functionalities based on a biodegradable polyphosphoester block copolymer system and showed high biocompatibility, with even the cationic micelles exhibiting a 6-fold lower cytotoxicity toward RAW 264.7 mouse macrophage cells.
Journal ArticleDOI
Self-Assembled Micelles of Biodegradable Triblock Copolymers Based on Poly(ethyl ethylene phosphate) and Poly(∈-caprolactone) as Drug Carriers
TL;DR: The in vitro degradation characteristics of the triblock copolymer micelles were investigated in micellar form, showing that these copolymers were completely biodegradable under enzymatic catalysis of Pseudomonas lipase and phosphodiesterase I.
Journal ArticleDOI
Main-chain poly(phosphoester)s: History, syntheses, degradation, bio-and flame-retardant applications
TL;DR: A comprehensive review summarizes synthetic protocols to poly(phosphoester) polymers, their applications in biomedicine, eg, as biodegradable drug carrier or in tissue engineering, and their flame retardant properties.
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Functional biodegradable polymers via ring-opening polymerization of monomers without protective groups.
Greta Becker,Frederik R. Wurm +1 more
TL;DR: An insight is given into available, orthogonally reactive cyclic monomers and the corresponding functional synthetic and biodegradable polymers, obtained from ROP, and post-modification strategies for the reported functionalities.
References
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Journal ArticleDOI
Hydrogels for tissue engineering: scaffold design variables and applications.
Jeanie L. Drury,David J. Mooney +1 more
TL;DR: Hydrogels are an appealing scaffold material because they are structurally similar to the extracellular matrix of many tissues, can often be processed under relatively mild conditions, and may be delivered in a minimally invasive manner.
Journal ArticleDOI
Why do phospholipid polymers reduce protein adsorption
Kazuhiko Ishihara,Hiroto Nomura,Hiroto Nomura,Takashi Mihara,Takashi Mihara,Kimio Kurita,Yasuhiko Iwasaki,Nobuo Nakabayashi +7 more
TL;DR: It is concluded that fewer proteins are adsorbed and their original conformation is not changed on polymer surfaces that possess a high free water fraction.
Journal ArticleDOI
Preparation of phospholipid polymers and their properties as polymer hydrogel membranes.
TL;DR: A methacrylate monomer having the phospholipid polar group, 2-methacryloyloxyethyl phosphorylcholine (MPC) was prepared by an improved method with good yield as mentioned in this paper.
Journal ArticleDOI
Raman Spectroscopic Study on the Structure of Water in Aqueous Polyelectrolyte Solutions
TL;DR: The structure and hydrogen bonding of water in various kinds of aqueous polyelectrolyte solutions were analyzed with contours of O−H stretching of polarized Raman spectra as discussed by the authors.
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