Journal ArticleDOI
o-Nitrobenzyl Alcohol Derivatives: Opportunities in Polymer and Materials Science
TLDR
The use of o-nitrobenzyl group (o-NB) in polymer chemistry has been extensively studied in this article, including the use of O-NB-based cross-linkers for photodegradable hydrogels, o-NB side chain functionalization in (block) copolymers, and oNB functionalization for thin film patterning for self-assembled monolayers.Abstract:
Polymers featuring photolabile groups are the subject of intense research because they allow the alteration of polymer properties simply by irradiation. In particular, the o-nitrobenzyl group (o-NB) is utilized frequently in polymer and materials science. This Perspective pays particular attention to the increasing utilization of this chemical group in polymer chemistry. It covers the use of (i) o-NB-based cross-linkers for photodegradable hydrogels, (ii) o-NB side chain functionalization in (block) copolymers, (iii) o-NB side chain functionalization for thin film patterning, (iv) o-NB for self-assembled monolayers, (v) photocleavable block copolymers, and (vi) photocleavable bioconjugates. We conclude with an outlook on new research directions in this rapidly expanding area.read more
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Journal ArticleDOI
Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy
Petr Klán,Tomáš Šolomek,Christian G. Bochet,Aurélien Blanc,Richard S. Givens,Marina Rubina,Vladimir V. Popik,Alexey Kostikov,Jakob Wirz +8 more
TL;DR: The review covers the knowledge on photoremovable protecting groups and includes all relevant chromophores studied in the time period of 2000–2012 and the most relevant earlier works are discussed.
Journal ArticleDOI
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
Mahdi Karimi,Amir Ghasemi,Parham Sahandi Zangabad,Reza Rahighi,S. Masoud Moosavi Basri,S. Masoud Moosavi Basri,Hamed Mirshekari,Mandana Amiri,Z. Shafaei Pishabad,A. Aslani,Mahnaz Bozorgomid,Deepanjan Ghosh,Ali Beyzavi,A. Vaseghi,Amir Reza Aref,L. Haghani,Sajad Bahrami,Michael R. Hamblin,Michael R. Hamblin +18 more
TL;DR: This review highlights the recent advances of smart MNPs categorized according to their activation stimulus (physical, chemical, or biological) and looks forward to future pharmaceutical applications.
Journal ArticleDOI
Temperature- and light-responsive smart polymer materials
TL;DR: This present review wants to highlight the recent progress in the field of synthetic stimuli-responsive polymers combining temperature and light responsiveness.
Journal ArticleDOI
Photochromism into nanosystems: towards lighting up the future nanoworld.
Ling Wang,Quan Li +1 more
TL;DR: This Review provides an account of the recent advancements in reversible photocontrol of the structures and functions of photochromic nanosystems and their applications and outlines the challenges that need to be addressed and the opportunities that can be tapped into.
Journal ArticleDOI
Recent advances in stimuli-responsive degradable block copolymer micelles: synthesis and controlled drug delivery applications
Qian Zhang,Na Re Ko,Jung Kwon Oh +2 more
TL;DR: This review summarizes recent development of various strategies to the design and synthesis of self-assembled micellar aggregates based on novel amphiphilic block copolymers having different numbers of stimuli-responsive cleavable elements at various locations.
References
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TL;DR: In this paper, a set of powerful, highly reliable, and selective reactions for the rapid synthesis of useful new compounds and combinatorial libraries through heteroatom links (C-X-C), an approach called click chemistry is defined, enabled, and constrained by a handful of nearly perfect "springloaded" reactions.
Journal ArticleDOI
Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
April M. Kloxin,Andrea M. Kasko,Andrea M. Kasko,Chelsea N. Salinas,Chelsea N. Salinas,Kristi S. Anseth,Kristi S. Anseth +6 more
TL;DR: A strategy to create photodegradable poly(ethylene glycol)–based hydrogels through rapid polymerization of cytocompatible macromers for remote manipulation of gel properties in situ is reported.
Journal ArticleDOI
Biologically active molecules with a "light switch".
Günter Mayer,Alexander Heckel +1 more
TL;DR: This review summarizes new developments of the last five years and deals with "small molecules", proteins, and nucleic acids which can either be irreversibly activated with light (these compounds are referred to as "caged compounds") or reversibly switched between an active and an inactive state.
Journal ArticleDOI
Block copolymer based nanostructures: materials, processes, and applications to electronics.
TL;DR: A comparison study of how three different approaches to placement control of block Copolymer Ordering in Thin Films changed the quality of the films they produced.
Journal ArticleDOI
Surface-Directed Liquid Flow Inside Microchannels
TL;DR: The ability to confine liquid flow inside microchannels with only two physical walls is expected to be useful in applications where a large gas- liquid interface is critical, as demonstrated here by a gas-liquid reaction.