Journal ArticleDOI
Occurrence of geissoschizine and other minor biogenetically related alkaloids in Rhazya stricta
TLDR
Two more indolic bases, rhazinine and R1, were shown to be identical with antirhine and geissoschizine respectively and the biogenetic significance of the occurrence of the latter is discussed.About:
This article is published in Phytochemistry.The article was published on 1970-07-01. It has received 74 citations till now. The article focuses on the topics: Rhazya stricta & Rhazinilam.read more
Citations
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Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation
TL;DR: This tutorial review describes selected recent examples of how the metal-catalysed C-H bond functionalisation has been able to positively affect the synthesis of natural products.
Journal ArticleDOI
Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindle.
TL;DR: This review describes the biochemistry of tubulin, microtubules, and the mitotic spindle and describes the natural and synthetic agents which are known to interact with tubulin.
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C-H activation: a complementary tool in the total synthesis of complex natural products.
David Y.-K. Chen,So Won Youn +1 more
TL;DR: Recently completed total syntheses showcasing creative and ingenious incorporation of C-Hactivation as a strategic manoeuver are compared with their "non-C-H activation" counterparts, illuminating a new paradigm in strategic synthetic design.
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Pd-Catalyzed Chemoselective Catellani Ortho-Arylation of Iodopyrroles: Rapid Total Synthesis of Rhazinal
TL;DR: A Pd-catalyzed chemoselective Catellani reaction of iodopyrroles was developed and led to the rapid synthesis of rhazinal in a highly efficient manner.
Journal ArticleDOI
Phytochemical, pharmacological and ethnobotanical studies of Rhazya stricta Decne.
Syed Amir Gilani,Syed Amir Gilani,Akira Kikuchi,Zabta Khan Shinwari,Zafar Iqbal Khattak,Kazuo N. Watanabe +5 more
TL;DR: The genetic diversity, chemotaxonomy and allelopathy of R. stricta have not yet been explored, and these studies are recommended, with the ultimate goal of benefiting local communities in regions where the species grows.
References
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Alkaloids of Geissospermum vellosii. Further Studies on Geissospermine and the Structures of the Indolic Cleavage Products, Geissoschizine1 and Apogeissoschizine
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Antirhine, a new indole alkaloid from Antirhea putaminosa (F. Muell.) Bail. (family Rubiaceae)
TL;DR: Antirhine, the major alkaloid of Antirhea putaminosa (F. Muell.) Bail.