Osteoporosis in the European Union: a compendium of country-specific reports
Axel Svedbom,E Hernlund,M Ivergard,Juliet E. Compston,Cyrus Cooper,Cyrus Cooper,J Stenmark,Eugene V. McCloskey,Eugene V. McCloskey,Bengt Jönsson,John A. Kanis +10 more
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TLDR
In spite of the high cost of osteoporosis, a substantial treatment gap and projected increase of the economic burden driven by aging populations, the use of pharmacological prevention of osteeporosis has decreased in recent years, suggesting that a change in healthcare policy concerning the disease is warranted.Abstract:
This report describes epidemiology, burden, and treatment of osteoporosis in each of the 27 countries of the European Union (EU27). In 2010, 22 million women and 5.5 million men were estimated to have osteoporosis in the EU; and 3.5 million new fragility fractures were sustained, comprising 620,000 hip fractures, 520,000 vertebral fractures, 560,000 forearm fractures and 1,800,000 other fractures. The economic burden of incident and prior fragility fractures was estimated at € 37 billion. Previous and incident fractures also accounted for 1,180,000 quality-adjusted life years lost during 2010. The costs are expected to increase by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining. The aim of this report was to characterize the burden of osteoporosis in each of the EU27 countries in 2010 and beyond. The data on fracture incidence and costs of fractures in the EU27 were taken from a concurrent publication in this journal (Osteoporosis in the European Union: Medical Management, Epidemiology and Economic Burden) and country specific information extracted. The clinical and economic burden of osteoporotic fractures in 2010 is given for each of the 27 countries of the EU. The costs are expected to increase on average by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining. In spite of the high cost of osteoporosis, a substantial treatment gap and projected increase of the economic burden driven by aging populations, the use of pharmacological prevention of osteoporosis has decreased in recent years, suggesting that a change in healthcare policy concerning the disease is warranted.read more
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Brillouin spectroscopy and radiography for assessment of viscoelastic and regenerative properties of mammalian bones.
Dana Akilbekova,Vyacheslav Ogay,Talgat A. Yakupov,Madina Sarsenova,Bauyrzhan Umbayev,Asset Nurakhmetov,Kairat Tazhin,Vladislav V. Yakovlev,Zhandos N. Utegulov +8 more
TL;DR: Results showed that MCS and BPMs are critically important for regeneration of elastic and viscous properties, respectively, HCF gels containing combination of all factors had the best effect with complete defect regeneration at week nine after the implantation of bone grafts and that the bones with fully consolidated fractures have higher values of elastic moduli compared with defective bones.
Journal ArticleDOI
Cost-effective osteoporosis treatment thresholds in Greece
Polyzois Makras,Kostas Athanasakis,Nadia Boubouchairopoulou,Stavroula Rizou,Athanasios D. Anastasilakis,John Kyriopoulos,George P. Lyritis +6 more
TL;DR: Osteoporosis treatment may be facilitated in Greece if FRAX algorithm is used to identify subjects with 10-year probabilities for hip and major osteoporotic fractures under the age of 75, while for older patients, the relevant thresholds are 5 and 15 %, respectively.
Journal ArticleDOI
Unilateral versus bilateral percutaneous kyphoplasty for osteoporotic vertebral compression fractures: A systematic review and meta-analysis of RCTs
TL;DR: It is suggested that a unilateral PKP is advantageous for osteoporotic vertebral compression fractures and this research compared the efficacy and safety of unilateral versus bilateral PKP for OVCs.
Journal ArticleDOI
Epidemiology of forearm fractures in adults in Denmark: national age- and gender-specific incidence rates, ratio of forearm to hip fractures, and extent of surgical fracture repair in inpatients and outpatients
TL;DR: The rates of forearm fracture in Denmark are higher than previously estimated and very similar to the high risk reported from studies in Norway and Sweden.
Journal ArticleDOI
Bone mineral density in lifelong trained male football players compared with young and elderly untrained men.
Marie Hagman,Eva Wulff Helge,Therese Hornstrup,Bjørn Fristrup,Bjørn Fristrup,Jens Jung Nielsen,Niklas Rye Jørgensen,Jesper Løvind Andersen,Jørn Wulff Helge,Peter Krustrup,Peter Krustrup +10 more
TL;DR: BMD of the proximal femur and whole-body BMD are markedly higher in lifelong trained male football players aged 65–80 years and young elitefootball players aged 18–30 years compared to age-matched untrained men.
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Long-Term Risk of Osteoporotic Fracture in Malmö
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