Journal ArticleDOI
Oxidative damage of retinal rod outer segment membranes and the role of vitamin E.
Reads0
Chats0
TLDR
This work suggests that extensive precautions against oxidative degradation should also be employed in studies of other membrane systems where important deleterious effects of oxygen may be less obvious.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1976-09-07. It has received 211 citations till now. The article focuses on the topics: Membrane lipids & Biological membrane.read more
Citations
More filters
Journal ArticleDOI
The Role of Oxidative Stress in the Pathogenesis of Age-Related Macular Degeneration
TL;DR: The concept that AMD can be attributed to cumulative oxidative stress is enticing, but remains unproven, and the effect of nutritional antioxidant supplements on the onset and natural course of age-related macular disease is currently being evaluated.
Journal ArticleDOI
Chemistry and metabolism of lipids in the vertebrate retina
Journal Article
Aging human RPE: morphometric analysis of macular, equatorial, and peripheral cells.
TL;DR: The largest increase in lipofuscin granules occurred between the first and second decade of life, and further increases occurred with age, and these findings may serve as a baseline for estimating normalcy of human RPE specimens.
Book
Biochemistry of the Eye
TL;DR: Tears, Iris-Ciliary Body, and Trabeculum: Selected Topics in Biochemistry Relevant to the Eye.
Journal ArticleDOI
The antioxidant effects of thylakoid Vitamin E (α-tocopherol)
TL;DR: The importance of the Vitamin E-Vitamin C thylakoid antioxidant system is examined, in terms of susceptibility to photo-oxidative damage under stress conditions including chilling, ageing and senescence, drought, atmospheric pollutants, herbicides and photosensitizing fungal toxins.
References
More filters
Journal ArticleDOI
Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride–methanol
William R. Morrison,L.M. Smith +1 more
TL;DR: The procedure developed is simple, rapid, and generally applicable t o lipids, and the results did not affect the validity of the method.
Journal ArticleDOI
The thiobarbituric acid reaction and the autoxidations of polyunsaturated fatty acid methyl esters.
TL;DR: The mechanism of oxidation of methylene-interrupted trienes, tetraenes, pentaenes, and hexaenes postulates an additional step in chain propagation involving intramolecular rearrangement of the hydroperoxy free radical to a free radical bearing a closed five-membered ring peroxide.
Book ChapterDOI
Vitamin E as the Biological Lipid Antioxidant
TL;DR: This chapter discusses mechanism of free radical damage and cellular damage caused by lipid peroxidation, and outlines the interrelationships of sulphur amino acids, vitamin E, and free radicalperoxidation.