Journal ArticleDOI
Partial purification of the Ca2+-Mg2+ ATPase activator from human erythrocytes: its similarity to the activator of 3':5' - cyclic nucleotide phosphodiesterase.
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TLDR
Results suggest that the ATPase activator is closely related to Ca 2+ binding proteins from a number of sources, and to skeletal muscle troponin-C as well.About:
This article is published in Biochemical and Biophysical Research Communications.The article was published on 1977-08-22. It has received 374 citations till now. The article focuses on the topics: Activator (genetics) & ATPase.read more
Citations
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Calmodulin plays a pivotal role in cellular regulation
TL;DR: The role of calcium ions (Ca2+) in cell function is beginning to be unraveled at the molecular level as a result of recent research on calcium-binding proteins and particularly on calmodulin.
Journal ArticleDOI
The role of protein phosphorylation in neural and hormonal control of cellular activity
TL;DR: There is an integrated network of regulatory pathways, mediated by phosphorylation–dephosphorylation, that allows diverse cellular events to be coordinated by neural and hormonal stimuli, and the evidence that supports this concept is reviewed.
Journal ArticleDOI
Calmodulin—an intracellular calcium receptor
Anthony R. Means,John R. Dedman +1 more
TL;DR: Calmodulin, a protein that binds calcium with high affinity and specificity, is structurally conserved and functionally preserved throughout the animal and plant kingdoms.
Journal ArticleDOI
Calcium Pumps in Health and Disease
Marisa Brini,Ernesto Carafoli +1 more
TL;DR: The molecular understanding of the function of the pumps has received great impetus from the solution of the three-dimensional structure of one of them, the SERCA pump, which has paralleled the rapid expansion of knowledge in the topic of Ca2+-signaling dysfunction.
Journal ArticleDOI
Identification of the Ca2+-dependent modulator protein as the fourth subunit of rabbit skeletal muscle phosphorylase kinase.
Philip Cohen,Ann Burchell,J.Gordon Foulkes,Patricia T.W. Cohen,Thomas C. Vanaman,Anagus C. Nairin +5 more
TL;DR: The finding that the ‘modulator’ could substitute for troponin-C in restoring calcium sensitivity to actomyosin ATPase in reconstituted systems was substantiated by the determination of the amino acid sequence of the “calcium-dependent modulator” from bovine brain and rat testis.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Determination of serum proteins by means of the biuret reaction.
TL;DR: An investigation of the biochemical changes following experimental liver injury felt the need of a simple, rapid, and accurate method for determining the protein fractions in small amounts of serum and began with Kingsley’s biuret procedure.
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Methods of Biochemical Analysis
TL;DR: The Radiation Inactivation Method as a Tool to Study Structure-Function Relationships in Proteins Immunoassay with Electrochemical Detection and Theory and Newer Technology Assays for Superoxide Dismutase are studied.
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Molecular Weight Determination of Protein-Dodecyl Sulfate Complexes by Gel Electrophoresis in a Discontinuous Buffer System
TL;DR: The retardation coefficient is shown both empirically and theoretically to be a uniform function of molecular weight of protein-SDS complexes over specified ranges, providing a rationale for determining molecular weight from plots of the negative logarithm of relative mobility against molecular weight.
Journal ArticleDOI
Cyclic 3',5'-nucleotide phosphodiesterase. Evidence for and properties of a protein activator.
TL;DR: It was concluded that the residual activity associated with the purified enzyme was due to an incomplete removal of the activator from the enzyme.
Related Papers (5)
Cyclic 3',5'-nucleotide phosphodiesterase. Demonstration of an activator.
W Y Cheung,W Y Cheung +1 more