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Patient-ventilator asynchrony during assisted mechanical ventilation

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TLDR
One-fourth of patients exhibit a high incidence of asynchrony during assisted ventilation, which is associated with a prolonged duration of mechanical ventilation and with excessive levels of ventilatory support.
Abstract
Objective The incidence, pathophysiology, and consequences of patient-ventilator asynchrony are poorly known. We assessed the incidence of patient-ventilator asynchrony during assisted mechanical ventilation and we identified associated factors.

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Citations
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Neurally Adjusted Ventilatory Assist (NAVA): An Update and Summary of Experiences

TL;DR: Results demonstrate that NAVA maintains subject-ventilator synchrony, adapts to altered respiratory demand, and delivers tidal volumes and mean airway pressures that can be considered protective.
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Accuracy of Invasive and Noninvasive Parameters for Diagnosing Ventilatory Overassistance During Pressure Support Ventilation.

TL;DR: A respiratory rate of 17 breaths/min is the parameter with the greatest accuracy for diagnosing overassistance in adults under mechanical ventilation under pressure support ventilation.
Journal ArticleDOI

Reverse Trigger Phenotypes in Acute Respiratory Distress Syndrome.

TL;DR: Reverse triggering causes variable physiological effects, depending on the phenotype, and differentiation of phenotype effects may be important to understand the clinical impacts of these events.
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Respiratory support by neurally adjusted ventilatory assist (NAVA) in severe RSV-related bronchiolitis: a case series report.

TL;DR: The findings highlight the feasibility and benefit of NAVA in children with severe RSV-related bronchiolitis and provide a less aggressive ventilation requiring lower inspiratory pressures with good results for oxygenation and more comfort for the children.
References
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Journal ArticleDOI

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine.

TL;DR: The ESICM developed a so-called sepsis-related organ failure assessment (SOFA) score to describe quantitatively and as objectively as possible the degree of organ dysfunction/failure over time in groups of patients or even in individual patients.
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A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study

J R Le Gall, +2 more
- 22 Dec 1993 - 
TL;DR: The SAPS II, based on a large international sample of patients, provides an estimate of the risk of death without having to specify a primary diagnosis, and is a starting point for future evaluation of the efficiency of intensive care units.
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Inspiratory Pressure Support Prevents Diaphragmatic Fatigue during Weaning from Mechanical Ventilation

TL;DR: Pressure support ventilation can assist spontaneous breathing and avoid diaphragmatic fatigue in patients demonstrating difficulties in weaning from the ventilator and clinical monitoring of sternocleidomastoid muscle activity allows the required level of pressure support to be determined to prevent fatigue.
Journal ArticleDOI

Ventilator-induced Diaphragmatic Dysfunction

TL;DR: This Critical Care Perspective defines the phenomenon, henceforth referred to as ventilatorinduced diaphragmatic dysfunction (VIDD), as a loss of diaphRAGmatic force-generating capacity that is specifically related to the use of mechanical ventilation.
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Impact of PEEP on lung mechanics and work of breathing in severe airflow obstruction

TL;DR: Low levels of PEEP may improve lung mechanics and reduce the effort required of mechanically ventilated patients with severe airflow obstruction, without substantially increasing the hazards of hyperinflation.
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