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Patient-ventilator asynchrony during assisted mechanical ventilation

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TLDR
One-fourth of patients exhibit a high incidence of asynchrony during assisted ventilation, which is associated with a prolonged duration of mechanical ventilation and with excessive levels of ventilatory support.
Abstract
Objective The incidence, pathophysiology, and consequences of patient-ventilator asynchrony are poorly known. We assessed the incidence of patient-ventilator asynchrony during assisted mechanical ventilation and we identified associated factors.

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Citations
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Journal ArticleDOI

Monitoring of the Respiratory Muscles in the Critically Ill

TL;DR: In this perspective, practical issues and the absence of sound scientific data for clinical benefit should not discourage clinicians from having a closer look at respiratory muscle function in critically ill patients.
Journal ArticleDOI

Patient-ventilator asynchrony during noninvasive ventilation: a bench and clinical study.

TL;DR: In this paper, a clinical study evaluated the incidence of patient-ventilator asynchronies in 15 patients during three randomized, consecutive, 20-min periods of NIV using an ICU ventilator with and without its NIV algorithm engaged and a dedicated NIV ventilators.
Journal ArticleDOI

Proportional assist ventilation with load-adjustable gain factors in critically ill patients: comparison with pressure support

TL;DR: Compared to PS, PAV+ increases the probability of remaining on spontaneous breathing, while it considerably reduces the incidence of patient–ventilator asynchronies.
Journal ArticleDOI

Observational study of patient-ventilator asynchrony and relationship to sedation level.

TL;DR: Asynchrony is common, and deeper sedation level is a predictor of ineffective triggering, andeper levels of sedation were associated with increasing ITI.
Journal ArticleDOI

Ventilatory support in children with pediatric acute respiratory distress syndrome: proceedings from the Pediatric Acute Lung Injury Consensus Conference.

TL;DR: The Consensus Conference developed pediatric-specific recommendations regarding mechanical ventilation of the patient with pediatric acute respiratory distress syndrome as well as future research priorities to initiate discussion regarding optimal mechanical ventilation management and identify areas of controversy requiring further investigation.
References
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Journal ArticleDOI

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine.

TL;DR: The ESICM developed a so-called sepsis-related organ failure assessment (SOFA) score to describe quantitatively and as objectively as possible the degree of organ dysfunction/failure over time in groups of patients or even in individual patients.
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A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study

J R Le Gall, +2 more
- 22 Dec 1993 - 
TL;DR: The SAPS II, based on a large international sample of patients, provides an estimate of the risk of death without having to specify a primary diagnosis, and is a starting point for future evaluation of the efficiency of intensive care units.
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Inspiratory Pressure Support Prevents Diaphragmatic Fatigue during Weaning from Mechanical Ventilation

TL;DR: Pressure support ventilation can assist spontaneous breathing and avoid diaphragmatic fatigue in patients demonstrating difficulties in weaning from the ventilator and clinical monitoring of sternocleidomastoid muscle activity allows the required level of pressure support to be determined to prevent fatigue.
Journal ArticleDOI

Ventilator-induced Diaphragmatic Dysfunction

TL;DR: This Critical Care Perspective defines the phenomenon, henceforth referred to as ventilatorinduced diaphragmatic dysfunction (VIDD), as a loss of diaphRAGmatic force-generating capacity that is specifically related to the use of mechanical ventilation.
Journal ArticleDOI

Impact of PEEP on lung mechanics and work of breathing in severe airflow obstruction

TL;DR: Low levels of PEEP may improve lung mechanics and reduce the effort required of mechanically ventilated patients with severe airflow obstruction, without substantially increasing the hazards of hyperinflation.
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