Pediatric Extracorporeal Life Support Organization Registry International Report 2016.
Ryan P. Barbaro,Matthew L. Paden,Yigit S. Guner,Lakshmi Raman,Lindsay M. Ryerson,Peta M. A. Alexander,Viviane G. Nasr,Melania M. Bembea,Peter Rycus,Ravi R. Thiagarajan +9 more
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TLDR
Adverse events including neurologic events were common during ECLS, a fact that underscores the opportunity and need to promote quality improvement work.Abstract:
The purpose of this report is to describe the international growth, outcomes, complications, and technology used in pediatric extracorporeal life support (ECLS) from 2009 to 2015 as reported by participating centers in the Extracorporeal Life Support Organization (ELSO). To date, there are 59,969 children who have received ECLS in the ELSO Registry; among those, 21,907 received ECLS since 2009 with an overall survival to hospital discharge rate of 61%. In 2009, 2,409 ECLS cases were performed at 157 centers. By 2015, that number grew to 2,992 cases in 227 centers, reflecting a 24% increase in patients and 55% growth in centers. ECLS delivered to neonates (0-28 days) for respiratory support was the largest subcategory of ECLS among children <18-years old. Overall, 48% of ECLS was delivered for respiratory support and 52% was for cardiac support or extracorporeal life support to support cardiopulmonary resuscitation (ECPR). During the study period, over half of children were supported on ECLS with centrifugal pumps (51%) and polymethylpentene oxygenators (52%). Adverse events including neurologic events were common during ECLS, a fact that underscores the opportunity and need to promote quality improvement work.read more
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Postcardiotomy extracorporeal membrane oxygenation in patients with congenital heart disease; the effect of place of initiation.
TL;DR: In this paper , the authors compared postcardiotomy extracorporeal membrane oxygenation (ECMO) initiation in the operating room (OR) or the pediatric cardiac intensive care unit (PCICU) and evaluate risk factors for hospital mortality.
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Discretion Over Discrimination: Toward Good Decisions for Extracorporeal Membrane Oxygenation Use in Patients With Neurological Comorbidities.
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Coagulopathy Characterized by Rotational Thromboelastometry in a Porcine Pediatric ECMO Model.
Christopher R. Reed,Desiree Bonadonna,Jeffrey I. Everitt,Victoria Robinson,James C. Otto,Elisabeth T. Tracy +5 more
TL;DR: This model serves as an important means to study the complex derangements in hemostasis during ECMO and is demonstrated the feasibility of such a model while providing descriptions of physiologic, hematologic, and coagulation parameters throughout.
Book ChapterDOI
Circulatory Assist Devices in Heart Failure
TL;DR: Mechanically assisted circulation has become a mainstay in the treatment of acute and chronic advanced heart failure and durable, implantable ventricular assist devices for chronic support are now miniaturized and provide blood flow in a continuous rather than pulsatile manner.
Journal ArticleDOI
Extracorporeal Membrane Oxygenation Characteristics and Outcomes in Children and Adolescents With COVID-19 or Multisystem Inflammatory Syndrome Admitted to U.S. ICUs*
Melania M. Bembea,Laura Loftis,Ravi R. Thiagarajan,Cameron C Young,Timothy P. McCadden,Margaret M Newhams,Suden Kucukak,Elizabeth H. Mack,Julie C. Fitzgerald,Courtney M. Rowan,Aline B Maddux,Amanda Kolmar,Katherine Irby,Sabrina M. Heidemann,Stephanie P Schwartz,Michele Kong,Hillary Crandall,Kevin M Havlin,Aalok R. Singh,Jennifer E. Schuster,Mark A. Hall,Kari Wellnitz,Mia Maamari,Mary Glas Gaspers,Ryan Nofziger,Peter Paul Lim,Ryan W. Carroll,Alvaro Coronado Munoz,Tamara T. Bradford,Melissa Cullimore,Natasha B. Halasa,Gwenn E. McLaughlin,Pia S. Pannaraj,Natalie Z. Cvijanovich,Matt S. Zinter,Bria M. Coates,Steven M. Horwitz,Charlotte V. Hobbs,Heda Dapul,Ana Lia Graciano,Andrew D Butler,Manish M. Patel,Laura D. Zambrano,Angela P Campbell,Adrienne G. Randolph +44 more
TL;DR: In this article , extracorporeal membrane oxygenation (ECMO) has been used successfully to support adults with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related cardiac or respiratory failure refractory to conventional therapies.
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