Journal ArticleDOI
Polar effects in free radical reactions. Homolytic aromatic amination by the amino radical cation, .cntdot.+NH3: reactivity and selectivity
Attilio Citterio,Anna Gentile,Francesco Minisci,Valter Navarrini,Marco Serravalle,Susanna Ventura +5 more
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This article is published in Journal of Organic Chemistry.The article was published on 1984-11-01. It has received 49 citations till now. The article focuses on the topics: Radical-nucleophilic aromatic substitution & Amino radical.read more
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Distonic radical cations in gaseous and condensed phase
TL;DR: In this paper, the authors demontre que les radicaux cationiques CH 3 OH +, CH 3 NH 2 + and CH 3 ClH + ont des isomeres stables.
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Late-stage C-H functionalization offers new opportunities in drug discovery
TL;DR: In this paper, the authors provide a toolbox for chemists in academia as well as industrial practitioners, and introduce guiding principles for the application of late-stage functionalization strategies to access new molecules of interest.
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N-Aminopyridinium Salts as Precursors for N-Centered Radicals – Direct Amidation of Arenes and Heteroarenes
TL;DR: It is shown that direct radical C-H amination of heteroarenes and arenes can be achieved with N-aminopyridinium salts under mild conditions by using photoredox catalysis.
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A mild, ferrocene-catalyzed C-H imidation of (hetero)arenes.
TL;DR: Mechanistic studies indicate that ferrocene (Cp2Fe) plays the role of an electron shuttle in the decomposition of the perester reagent, delivering a succinimidyl radical ready to add to an aromatic system.
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Charge-transfer-directed radical substitution enables para-selective C–H functionalization
Gregory B. Boursalian,Gregory B. Boursalian,Won Seok Ham,Anthony R. Mazzotti,Tobias Ritter,Tobias Ritter +5 more
TL;DR: It is proposed that radicals with high electron affinity elicit areneto-radical charge transfer in the transition state of radical addition, which is the factor primarily responsible for high positional selectivity.