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Open AccessJournal ArticleDOI

Porous scaffolds for bone regeneration

TLDR
This review focuses on the relationship between the porosity and pore size of scaffolds and subsequent osteogenesis, vascularisation and scaffold degradation during bone regeneration.
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This article is published in Journal of Science: Advanced Materials and Devices.The article was published on 2020-03-01 and is currently open access. It has received 303 citations till now. The article focuses on the topics: Bone regeneration & Scaffold.

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Citations
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Scaffold fabrication technologies and structure/function properties in bone tissue engineering

TL;DR: A comprehensive review of the current accomplishments on scaffold fabrication techniques, their structure, and function properties for BTE is provided and strategies to improve vascularization potential and immunomodulation are presented.
Journal ArticleDOI

Bone tissue engineering techniques, advances and scaffolds for treatment of bone defects.

TL;DR: Recent advances in bone tissue engineering are highlighted, with particular emphasis on the role of the biomaterials as scaffolding material to heal bone defects.
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Powder metallurgy with space holder for porous titanium implants: A review

TL;DR: In this article, powder metallurgy with space holder (SH) is a powerful technology used to produce porous Ti structures, it is discussed its potential for the fabrication of medical devices from the perspectives of both design and manufacture.
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Chitosan-based 3D-printed scaffolds for bone tissue engineering

TL;DR: In this paper, the physicochemical-biological properties and applications of chitosan-based 3D-printed scaffolds and their future perspectives in BTE are summarized.
References
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Journal ArticleDOI

Matrix elasticity directs stem cell lineage specification.

TL;DR: Naive mesenchymal stem cells are shown here to specify lineage and commit to phenotypes with extreme sensitivity to tissue-level elasticity, consistent with the elasticity-insensitive commitment of differentiated cell types.
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Porous scaffold design for tissue engineering

TL;DR: The integration of CTD with SFF to build designer tissue-engineering scaffolds is reviewed and the mechanical properties and tissue regeneration achieved using designer scaffolds are details.
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The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering

TL;DR: The results show that cell number was highest in scaffolds with the largest pore size, which was deemed optimal for bone tissue engineering, and an added advantage of the larger pores is a reduction in cell aggregations that develop along the edges of the scaffolds.
Journal ArticleDOI

The effect of pore size on cell adhesion in collagen-GAG scaffolds.

TL;DR: The strong correlation between the scaffoldspecific surface area and cell attachment indicates that cell attachment and viability are primarily influenced by scaffold specific surface area over this range (95.9-150.5 microm) of pore sizes for MC3T3 cells.
Journal ArticleDOI

An overview and management of osteoporosis

TL;DR: Increasing awareness among doctors, which, in turn, facilitates increase awareness of the normal populace, will be effective in preventing this epidemic of osteoporosis.
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How to examine scaffolds used for bone regeneration?

The relationship between the porosity and pore size of scaffolds and subsequent osteogenesis, vascularisation, and scaffold degradation during bone regeneration is examined in this review.