Predicting morbidity and mortality in acute pancreatitis in an Indian population: a comparative study of the BISAP score, Ranson’s score and CT severity index
Jitin Yadav,Sanjay Kumar Yadav,Satish Kumar,Ranjan George Baxla,Dipendra Kumar Sinha,Pankaj Bodra,Ram Chandra Besra,Babu Mani Baski,Om Prakash,Abhinav Anand +9 more
TLDR
The BISAP score represents a simple way of identifying, within 24 hours of presentation, patients at greater risk of dying and the development of intermediate markers of severity, in a tertiary care centre in east central India.Abstract:
Objective: Our aim was to prospectively evaluate the accuracy of the bedside index for severity in acute pancreatitis (BISAP) score in predicting mortality, as well as intermediate markers of severity, in a tertiary care centre in east central India, which caters mostly for an economically underprivileged population. Methods: A total of 119 consecutive cases with acute pancreatitis were admitted to our institution between November 2012 and October 2014. BISAP scores were calculated for all cases, within 24 hours of presentation. Ranson’s score and computed tomography severity index (CTSI) were also established. The respective abilities of the three scoring systems to predict mortality was evaluated using trend and discrimination analysis. The optimal cut-off score for mortality from the receiver operating characteristics (ROC) curve was used to evaluate the development of persistent organ failure and pancreatic necrosis (PNec). Results: Of the 119 cases, 42 (35.2%) developed organ failure and were classified as severe acute pancreatitis (SAP), 47 (39.5%) developed PNec, and 12 (10.1%) died. The area under the curve (AUC) results for BISAP score in predicting SAP, PNec, and mortality were 0.962, 0.934 and 0.846, respectively. Ranson’s score showed a slightly lower accuracy for predicting SAP (AUC 0.956) and mortality (AUC 0.841). CTSI was the most accurate in predicting PNec, with an AUC of 0.958. The sensitivity and specificity of BISAP score, with a cut-off of � 3 in predicting mortality, were 100% and 69.2%, respectively. Conclusions: The BISAP score represents a simple way of identifying, within 24 hours of presentation, patients at greater risk of dying and the development of intermediate markers of severity. This risk stratification method can be utilized to improve clinical care and facilitate enrolment in clinical trials.read more
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The early prediction of mortality in acute pancreatitis : a large population-based study. Commentary
Peter Layer,Bechien U. Wu,Richard S. Johannes,Xiaowu Sun,Ying P. Tabak,Darwin L. Conwell,Peter A. Banks +6 more
TL;DR: In this article, a clinical scoring system was developed for prediction of in-hospital mortality in acute pancreatitis using Classification and Regression Tree (CART) analysis, which was derived on data collected from 17 992 cases of AP from 212 hospitals in 2000-2001.
Journal ArticleDOI
A comparison of APACHE II, BISAP, Ranson’s score and modified CTSI in predicting the severity of acute pancreatitis based on the 2012 revised Atlanta Classification
TL;DR: APACHE II is a useful prognostic scoring system for predicting the severity of acute pancreatitis and can be a crucial aid in determining the group of patients that have a high chance of need for tertiary care during the course of their illness and therefore need early resuscitation and prompt referral, especially in resource-limited developing countries.
Journal ArticleDOI
Computed Tomography Severity Index vs. Other Indices in the Prediction of Severity and Mortality in Acute Pancreatitis: A Predictive Accuracy Meta-analysis
Alexandra Mikó,Éva Vigh,Péter Mátrai,Péter Mátrai,Alexandra Soós,Alexandra Soós,András Garami,Márta Balaskó,László Czakó,Bernadett Mosdósi,Patrícia Sarlós,Bálint Erőss,Judit Tenk,Ildikó Rostás,Péter Hegyi,Péter Hegyi +15 more
TL;DR: Though APACHE II is the most accurate predictor of mortality, CTSI is a good predictor of both mortality and AP severity, which should be used more often in routine clinical practice.
Journal ArticleDOI
An Artificial Neural Networks Model for Early Predicting In-Hospital Mortality in Acute Pancreatitis in MIMIC-III.
TL;DR: Wang et al. as discussed by the authors developed an artificial neural networks (ANN) model for early prediction of in-hospital mortality in acute pancreatitis in patients with MIMIC-III database.
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The Bedside Index for Severity in Acute Pancreatitis: a systematic review of prospective studies to determine predictive performance.
TL;DR: The BISAP has very good predictive performance for SAP across different patient population and etiologies, and studies to evaluate the impact of incorporating the B ISAP into clinical practice to improve outcome in acute pancreatitis are needed before adoption could be advocated with confidence.
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A prospective study of the Bedside Index for Severity in Acute Pancreatitis (BISAP) score in acute pancreatitis: An Indian perspective
Debadutta Senapati,Prasanna Kumar Debata,Saumya Sekhar Jenasamant,Anil Kumar Nayak,S Manoj Gowda,Narendra Nath Swain +5 more
TL;DR: The ability of BISAP score to predict mortality in acute pancreatitis patients from an institution and to predict which patients are at risk for development of organ failure, persistent organ failure and pancreatic necrosis was evaluated.
Journal ArticleDOI
[Bedside index for severity in acute pancreatitis (BISAP) score as predictor of clinical outcome in acute pancreatitis: retrospective review of 128 patients]
TL;DR: BISAP score was a useful method for predicting the severity of PA, with the advantage of being simple and based on parameters obtained on the first day of hospitalization, which was superior to APACHE II and Balthazar score in this cohort.