Prenatal exposure to pbdes and neurodevelopment
Julie B. Herbstman,Andreas Sjödin,Matthew Kurzon,Sally Ann Lederman,Richard S. Jones,Virginia Rauh,Larry L. Needham,Deliang Tang,Megan M. Niedzwiecki,Richard Y. Wang,Frederica P. Perera +10 more
TLDR
This epidemiologic study demonstrates neurodevelopmental effects in relation to cord blood PBDE concentrations, and indicates that children with higher concentrations of BDEs 47, 99, or 100 scored lower on tests of mental and physical development at 12–48 and 72 months.Abstract:
BackgroundPolybrominated diphenyl ethers (PBDEs) are widely used flame retardant compounds that are persistent and bioaccumulative and therefore have become ubiquitous environment contaminants. Ani...read more
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The Lancet Commission on pollution and health
Philip J. Landrigan,Richard Fuller,Nereus J R Acosta,Olusoji Adeyi,Robert G. Arnold,Niladri Basu,Abdoulaye Bibi Baldé,Roberto Bertollini,Stephan Bose-O'Reilly,Stephan Bose-O'Reilly,Jo Ivey Boufford,Patrick N. Breysse,Thomas C. Chiles,Chulabhorn Mahidol,Awa M Coll-Seck,Maureen L. Cropper,Julius N. Fobil,Valentin Fuster,Valentin Fuster,Michael Greenstone,Andy Haines,David Hanrahan,David J. Hunter,Mukesh Khare,Alan Krupnick,Bruce P. Lanphear,Bindu Lohani,Keith Martin,Karen V Mathiasen,Maureen A. McTeer,Christopher J L Murray,Johanita D Ndahimananjara,Frederica P. Perera,Janez Potočnik,Alexander S Preker,Alexander S Preker,Jairam Ramesh,Johan Rockström,Carlos Salinas,Leona D. Samson,Karti Sandilya,Peter D. Sly,Kirk R. Smith,Achim Steiner,Richard B. Stewart,William A. Suk,Onno C. P. van Schayck,Gautam N. Yadama,Kandeh K. Yumkella,Ma Zhong +49 more
TL;DR: This book is dedicated to the memory of those who have served in the armed forces and their families during the conflicts of the twentieth century.
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EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
Andrea C. Gore,Vesna A. Chappell,Suzanne E. Fenton,Jodi A. Flaws,Angel Nadal,Gail S. Prins,Jorma Toppari,R. T. Zoeller +7 more
TL;DR: A much more complete understanding of the endocrine principles by which EDCs act, including nonmonotonic dose-responses, low-dose effects, and developmental vulnerability, can be much better translated to human health.
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Neurobehavioural effects of developmental toxicity
TL;DR: To control the pandemic of developmental neurotoxicity, a global prevention strategy is proposed and chemicals in existing use and all new chemicals must therefore be tested for developmental neurotoxicants is proposed.
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Endocrine disrupting chemicals and disease susceptibility.
TL;DR: This review focuses on the mechanisms and modes of action by which EDCs alter hormone signaling, and includes brief overviews of select disease endpoints associated with endocrine disruption.
Journal ArticleDOI
Environmental chemicals in pregnant women in the United States: NHANES 2003-2004.
TL;DR: Biomonitoring data from the National Health and Nutritional Examination Survey (NHANES) found that levels in pregnant women were similar to or lower than levels in nonpregnant women; adjustment for covariates tended to increase levels innant women compared with nonpRegnant women.
References
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Journal ArticleDOI
An overview of brominated flame retardants in the environment.
TL;DR: In this paper, the current state of knowledge is reviewed and areas for further research recommended to improve future monitoring and risk assessment efforts, and the authors suggest that the occurrence of high concentrations of certain PBDE isomers may be sufficient to elicit adverse effects in some wildlife.
Journal ArticleDOI
Polybrominated Diphenyl Ethers in the Environment and in People: A Meta-Analysis of Concentrations
TL;DR: It is clear that the environment and people from North America are very much more contaminated with PBDEs as compared to Europe and that these PBDE levels have doubled every 4-6 yr.
Journal ArticleDOI
Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology.
TL;DR: Based on the scientific knowledge of today and based on Nordic intake data, the possible consumer health risk from PBDEs appears limited, as a factor of over 10 separates the estimated present mean dietary intake from the suggested LOAEL value.
Journal ArticleDOI
Human internal and external exposure to PBDEs – A review of levels and sources
TL;DR: This paper reviews the existing literature on human exposure to polybrominated diphenyl ethers, with particular focus on external exposure routes (e.g. dust, diet, and air) and the resulting internal exposure to PBDEs and shows that BDE-209 also accumulates in humans.
Journal ArticleDOI
Developmental neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants
Lucio G. Costa,Gennaro Giordano +1 more
TL;DR: Levels of PBDEs causing developmental neurotoxicity in animals are not much dissimilar from levels found in highly exposed infants and toddlers, and these levels have been increasing in the past 30 years.
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