Journal ArticleDOI
Prenylated xanthones and benzophenones from the fruits of Garcinia bracteata and their potential antiproliferative and anti-inflammatory activities.
Qing Xue,Yu Chen,Huijun Yin,Haida Teng,Rui Qin,Hong Liu,Qingqing Li,Zhinan Mei,Guangzhong Yang +8 more
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TLDR
Ten previously undescribed compounds, including five prenylated xanthones, two caged xanthone bearing a rare 8, 8a-epoxy moiety and three rearranged benzophenones, together with nineteen known compounds were isolated from the fruits of Garcinia bracteata to enrich the structural diversities ofxanthones and Benzophenones from Garcinia plants.About:
This article is published in Bioorganic Chemistry.The article was published on 2020-11-01. It has received 14 citations till now. The article focuses on the topics: Xanthone & Garcinia.read more
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Cytotoxic and Antiangiogenetic Xanthones Inhibiting Tumor Proliferation and Metastasis from Garcinia xipshuanbannaensis.
Xuke Zhang,Ziteng Song,Ying Li,Huimei Wang,Shaojie Zhang,Anna-Mari Reid,Namrita Lall,Jie Zhang,Chunyan Wang,Dongho Lee,Yasushi Ohizumi,Jing Xu,Yuanqiang Guo +12 more
TL;DR: In this article, eight prenylated xanthones including four new analogues were extracted and purified from the leaves of Garcinia xipshuanbannaensis and evaluated for their cytotoxicity toward human cancer cells, and compound 4 exhibited activity against HeLa cells.
Journal ArticleDOI
Two Antimicrobial Heterodimeric Tetrahydroxanthones with a 7,7′-Linkage from Mangrove Endophytic Fungus Aspergillus flavus QQYZ
TL;DR: This research enriched the resources of lead compounds and templates for marine-derived antimicrobial drugs by isolated two novel heterodimeric tetrahydroxanthones from the mangrove endophytic fungus Aspergillus flavus QQYZ.
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Structural diversity and biological activities of caged Garcinia xanthones: recent updates
Yee Lin Phang,Changwu Zheng +1 more
TL;DR: This review summarizes recent progress and development in the chemistry and biological activity of caged Garcinia xanthones and of several compounds of non-Garcinia origin, from the years 2008 to 2021, providing an in-depth discussion of their structural diversity and medicinal potential.
Journal ArticleDOI
A natural xanthone suppresses lung cancer growth and metastasis by targeting STAT3 and FAK signaling pathways.
TL;DR: Xipsxanthone H was obtained by various chromatography methods (including silica gel, medium pressure liquid chromatography (MPLC), and preparative high-performance liquid Chromatography (HPLC) as mentioned in this paper .
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The natural compound from Garcinia bracteata mainly induces GSDME-mediated pyroptosis in esophageal cancer cells.
Jiaqi Tan,Zhuo Li,Gan Chen,Man Wu,Jiling Feng,Siyuan Kong,Xiaoqin Shi,Hongmei Zhang,Yuanzhi Lao,Hua Zhou,Li Zhang,Hong-Xi Xu +11 more
TL;DR: Wu et al. as mentioned in this paper investigated whether GSDME-mediated pyroptosis contributes to NBT-induced antitumor effects in esophageal cancer (EC) cells.
References
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Journal ArticleDOI
Polycyclic Polyprenylated Acylphloroglucinols
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Research Progress of Polycyclic Polyprenylated Acylphloroglucinols.
TL;DR: The progress of research into the chemistry and biological activity of 421 natural PPAPs in the past 11 years as well as in-depth studies of biological activities and total synthesis of somePPAPs isolated before 2006 are discussed.
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Structural diversity and bioactivities of natural benzophenones.
TL;DR: This work will review natural benzophenones and provide an in-depth discussion of their structural diversity and biological activity, and select examples mostly from the last 15 years, but extending the scope to other historically important benzophenone discovered prior to that time.
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Antimicrobial and cytotoxic agents from Calophyllum inophyllum.
Marie C. Yimdjo,Anatole Guy Blaise Azebaze,Augustin Ephraim Nkengfack,A. Michele Meyer,Bernard Bodo,Zacharias Tanee Fomum +5 more
TL;DR: 12 known compounds of xanthone derivative, named inoxanthone, together with their structures were established on the basis of spectral evidence and their antibacterial activity and potency against a wide range of micro organisms were evaluated.
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An overview on genus garcinia : phytochemical and therapeutical aspects
Mahadevappa Hemshekhar,K. Sunitha,M. Sebastin Santhosh,S. Devaraja,Kempaiah Kemparaju,Bannikuppe S. Vishwanath,Siddapura Ramachandrappa Niranjana,Kesturu S. Girish +7 more
TL;DR: The genus Garcinia belongs to the family Clusiaceae and has been involved in ayurvedic preparations to medicate various pathophysiological disorders and bioactive molecules like hydroxycitric acid, flavonoids, terpenes, polysaccharides, procyanidines and polyisoprenylated benzophenone derivatives like garcinol, xanthochymol and guttiferone isoforms have been isolated.