Journal ArticleDOI
Preparation, characterization and biocompatibility studies on risperidone-loaded solid lipid nanoparticles (SLN): High pressure homogenization versus ultrasound
Ana Catarina Silva,E. González-Mira,Maria Luisa García,M.A. Egea,J.L.C. Fonseca,R. Silva,Delfim Santos,Eliana B. Souto,Eliana B. Souto,Domingos Ferreira +9 more
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TLDR
It is concluded that SLN can be considered as efficient carriers for RISP encapsulation and HPH and US revealed to be both effective methods for SLN production.About:
This article is published in Colloids and Surfaces B: Biointerfaces.The article was published on 2011-08-01. It has received 232 citations till now. The article focuses on the topics: Solid lipid nanoparticle.read more
Citations
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Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application.
TL;DR: A wide discussion about preparation methods, advantages, disadvantages and applications of LNPs is presented by focusing on SLNs and NLCs, two major types of Lipid-based nanoparticles.
Journal ArticleDOI
Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: applications, advantages and disadvantages.
TL;DR: The aim of this article is to review the advantages and limitations of these delivery systems based on the route of administration and to emphasis the effectiveness of such formulations.
Journal ArticleDOI
Double emulsion solvent evaporation techniques used for drug encapsulation
TL;DR: In this review special attention has been paid to the application of double emulsion techniques for the encapsulation of various hydrophilic and hydrophobic anticancer drugs, anti-inflammatory drugs, antibiotic drugs, proteins and amino acids and their applications in theranostics.
Journal ArticleDOI
Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release
TL;DR: The importance of obtaining a detailed knowledge of the structure of the lipid nanoparticles is highlighted, which is useful for the rational design of this type of nanocarriers and propose solutions to the challenges involved in their formulation.
Journal ArticleDOI
Solid lipid nanoparticles as attractive drug vehicles: Composition, properties and therapeutic strategies
TL;DR: This work briefly reviews up-to-date developments in solid lipid nanoparticles (SLNs) as effective nanocolloidal system for drug delivery and summarizes SLNs in terms of their preparation, surface modification and properties.
References
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Journal ArticleDOI
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
TL;DR: A tetrazolium salt has been used to develop a quantitative colorimetric assay for mammalian cell survival and proliferation and is used to measure proliferative lymphokines, mitogen stimulations and complement-mediated lysis.
Journal ArticleDOI
Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art.
TL;DR: Relevant issues for the introduction of SLN to the pharmaceutical market, such as status of excipients, toxicity/tolerability aspects and sterilization and long-term stability including industrial large scale production are discussed.
Journal ArticleDOI
Solid lipid nanoparticles: Production, characterization and applications
W. Mehnert,Karsten Mäder +1 more
TL;DR: An overview about the selection of the ingredients, different ways of SLN production and SLN applications, and the in vivo fate of the carrier are presented.
Journal ArticleDOI
Solid lipid nanoparticles for parenteral drug delivery.
TL;DR: The biological activity of parenterally applied SLN and biopharmaceutical aspects such as pharmacokinetic profiles as well as toxicity aspects are reviewed.
Journal ArticleDOI
Classification of orally administered drugs on the World Health Organization Model list of Essential Medicines according to the biopharmaceutics classification system.
TL;DR: In this report, orally administered drugs on the Model list of Essential Medicines of the World Health Organization (WHO) are assigned BCS classifications on the basis of data available in the public domain.
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