Journal ArticleDOI
Primary neural precursor cell expansion, differentiation and cytosolic Ca2+ response in three-dimensional collagen gel
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TLDR
Findings suggest the suitability of the 3D culture system for the proliferation and differentiation of neural precursor cells.About:
This article is published in Journal of Neuroscience Methods.The article was published on 2000-10-30. It has received 95 citations till now. The article focuses on the topics: Neurosphere & Neuroepithelial cell.read more
Citations
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Journal ArticleDOI
Inkjet printing of viable mammalian cells.
TL;DR: The computer-aided inkjet printing of viable mammalian cells holds potential for creating living tissue analogs, and may eventually lead to the construction of engineered human organs.
Book ChapterDOI
3D cell culture: a review of current approaches and techniques.
TL;DR: The intention of this review is to provide a general overview of the common approaches and techniques for designing 3D culture models and range from engineering tissues for clinical delivery through to the development of models for drug screening.
Journal ArticleDOI
Three-dimensional growth and function of neural tissue in degradable polyethylene glycol hydrogels.
TL;DR: In this article, the authors used confocal microscopy to non-invasively monitor these key cell functions over time, and showed that neural cells cultured within three-dimensional polymer networks create their own cellular microenvironment to survive, proliferate and differentiate and form neurons and glia that are electrophysiologically responsive to neurotransmitter.
Journal ArticleDOI
Neurotransmitters as early signals for central nervous system development
Laurent Nguyen,Jean-Michel Rigo,Véronique Rocher,Shibeshih Belachew,Brigitte Malgrange,Bernard Rogister,Pierre Leprince,Gustave Moonen +7 more
TL;DR: It is argued that neurotransmitters could regulate morphogenetic events such as proliferation, growth, migration, differentiation and survival of neural precursor cells, and could lead to the development of pharmacological tools aimed at improving adult brain repair strategies.
Journal ArticleDOI
Tissue engineering: current state and perspectives.
Erin B. Lavik,Robert Langer +1 more
TL;DR: This approach seeks to promote an environment which permits the native capacity of cells to integrate, differentiate, and develop new tissues which promote the development of new tissues whose properties more closely match their native counterparts.
References
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Journal ArticleDOI
Mammalian neural stem cells.
TL;DR: Before the full potential of neural stem cells can be realized, the authors need to learn what controls their proliferation, as well as the various pathways of differentiation available to their daughter cells.
Journal ArticleDOI
Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
TL;DR: High survival was achieved with osmolarity lower than found in Dulbecco's Modified Eagle's Medium (DMEM), and by reducing cysteine and glutamine concentrations and by the elimination of toxic ferrnous sulphate found in DME/F12, and Neurobasal is a new medium that incorporates modifications to DMEM.
Book
The Biomedical Engineering Handbook
TL;DR: Physiological systems bioelectric phenomena biomechanics biomaterials biosensors biomedical signal analysis imaging medical instruments and devices biological effects of non-ionizing biotechnology tissue engineering human performance engineering physiological modelling, simulation and control clinical engineering and artificial intelligence.
Journal ArticleDOI
Stem cells in the central nervous system.
TL;DR: The development of therapies for the reconstruction of the diseased or injured brain will be guided by the understanding of the origin and stability of cell type in the central nervous system.
Journal ArticleDOI
Collagen – biomaterial for drug delivery
TL;DR: Information available on collagen dosage forms for drug delivery as well as to impart an overview of the chemical structures and the galenical properties including detailed description of the processing steps - extraction, purification, chemical crosslinking and sterilization are summarized.