Journal ArticleDOI
Primate evolution of the α-globin gene cluster and its Alu-like repeats
Ikuhisa Sawada,Carl W. Schmid +1 more
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TLDR
The arrangement of alpha-globin genes in Old World and New World monkeys and a prosimian, galago, has been determined by restriction mapping and Orthologous Alu family members in human and monkey DNAs indicate that the dispersion of some Alu repeats occurred prior to the divergence of these lineages.About:
This article is published in Journal of Molecular Biology.The article was published on 1986-12-20. It has received 44 citations till now. The article focuses on the topics: Galago & Alu element.read more
Citations
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Journal ArticleDOI
Evolution of the master Alu gene(s)
TL;DR: This analysis confirmed that the formation of each subfamily can be explained by the sequential accumulation of mutations relative to the previous subfamily, and suggested that the vast majority of Alu elements amplified at any given time comprised a single Alu subfamily.
Journal ArticleDOI
Genetic variation of recent Alu insertions in human populations
Mark A. Batzer,Santosh S. Arcot,Joshua W. Phinney,Michelle Alegria-Hartman,David H. Kass,Stephen M. Milligan,C. P. Kimpton,Peter Gill,Manfred N. Hochmeister,Panayiotis A. Ioannou,Rene J. Herrera,Donald A. Boudreau,W. Douglas Scheer,Bronya J.B. Keats,Prescott L. Deininger,Mark Stoneking +15 more
TL;DR: The results indicate that these polymorphic Alu insertions probably have an African origin and that there is a much smaller amount of genetic variation between European populations than that found between other populations groups.
Book ChapterDOI
Alu: Structure, Origin, Evolution, Significance, and Function of One-Tenth of Human DNA
TL;DR: This chapter focuses on Alu repeats, a young Alu subfamily that appeared by simple drift of its founder, providing a model for the continual turnover of active repeat-sequence families.
Book ChapterDOI
Evolution of Retroposons
TL;DR: The retroposons represent interspersed repeated elements that apparently have amplified via an RNA intermediate (Jagadeeswaran et al., 1981) [reviewed in Rogers (1983, 1985 and Weiner et al. (1986)], but do not code for any proteins that may aid the amplification process.
Journal ArticleDOI
Evolution of chromosome bands: molecular ecology of noncoding DNA.
TL;DR: Theories of hierarchical selection and molecular ecology show how selection can act on Darwinian units of noncoding DNA at the genome level thus creating positionally constrained DNA and contributing minimal genetic load at the individual level.
References
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Journal ArticleDOI
Screening lambdagt recombinant clones by hybridization to single plaques in situ
WD Benton,Ronald W. Davis +1 more
TL;DR: A rapid, direct method for screening single plaques of Agt recombinant phage is described, which allows at least 10(6) clones to be screened per day and simplifies physical containment of recombinants.
Journal ArticleDOI
Repeated Sequences in DNA
Roy J. Britten,D. E. Kohne +1 more
TL;DR: Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms and used in medicine, science, and engineering.
Journal ArticleDOI
A general method for isolation of high molecular weight DNA from eukaryotes
Nikolaus Blin,Darrel W. Stafford +1 more
TL;DR: A new method for isolation of high molecular weight DNA from eukaryotes is presented, which allows preparation of DNA from a variety of tissues and from cells which were more difficult to lyse until now.
Journal ArticleDOI
Transcription termination and 3' processing: the end is in site!
TL;DR: In this article, it was shown that 3' cleavage of pre-mRNA in eukaryotes is, in many ways, the phenotypic equivalent of transcription termi-nation.
Book ChapterDOI
Gel electrophoresis of restriction fragments.
TL;DR: Gel electrophoresis of restriction fragments of deoxyribonucleic acid (DNA) in agarose or polyacrylamide gels is discussed, which is often useful to identify a particular sequence in the DNA fragments separated by gel electrophoreis.