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Open AccessJournal ArticleDOI

Principles of Diffusion Tensor Imaging and Its Applications to Basic Neuroscience Research

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TLDR
Diffusion tensor imaging (DTI) is a recently developed MRI technique that can measure macroscopic axonal organization in nervous system tissues and several applications are introduced, including visualization of axonal tracts in myelin and axonal injuries as well as human brain and mouse embryonic development.
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This article is published in Neuron.The article was published on 2006-09-07 and is currently open access. It has received 1593 citations till now. The article focuses on the topics: Tractography & Diffusion MRI.

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Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network

TL;DR: The results demonstrate that resting-state functional connectivity reflects structural connectivity and that combining modalities can enrich the understanding of these canonical brain networks.
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Multiplexed echo planar imaging for sub-second whole brain fmri and fast diffusion imaging

TL;DR: The novel M-EPI pulse sequence resulted in a significantly increased temporal resolution for whole brain fMRI, and as such, this new methodology can be used for studying non-stationarity in networks and generally for expanding and enriching the functional information.
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Diffusion in brain extracellular space.

TL;DR: Experimental studies with the real-time iontophoresis method employing the cation tetramethylammonium in normal brain tissue improve the conception of ECS structure and the roles of glia and extracellular matrix in modulating the ECS microenvironment.
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MRI quantification of non-Gaussian water diffusion by kurtosis analysis.

TL;DR: It is argued that the diffusional kurtosis is sensitive to diffusional heterogeneity and suggested that DKI may be useful for investigating ischemic stroke and neuropathologies, such as Alzheimer's disease and schizophrenia.
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Neuroplasticity subserving motor skill learning.

TL;DR: Findings demonstrating functional and structural plasticity across different spatial and temporal scales that mediate motor skill learning are reviewed while identifying converging areas of interest and possible avenues for future research.
References
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Book

The Mouse Brain in Stereotaxic Coordinates

TL;DR: The 3rd edition of this atlas is now in more practical 14"x11" format for convenient lab use and includes a CD of all plates and diagrams, as well as Adobe Illustrator files of the diagrams, and a variety of additional useful material.
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Spin diffusion measurements : spin echoes in the presence of a time-dependent field gradient

TL;DR: In this article, a derivation of the effect of a time-dependent magnetic field gradient on the spin-echo experiment, particularly in the presence of spin diffusion, is given.
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MR diffusion tensor spectroscopy and imaging.

TL;DR: Once Deff is estimated from a series of NMR pulsed-gradient, spin-echo experiments, a tissue's three orthotropic axes can be determined and the effective diffusivities along these orthotropic directions are the eigenvalues of Deff.
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The basis of anisotropic water diffusion in the nervous system – a technical review

TL;DR: The purpose of this review is to characterize the relationship of nuclear magnetic resonance measurements of water diffusion and its anisotropy (i.e. directional dependence) with the underlying microstructure of neural fibres.
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Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging.

TL;DR: It is shown that neuronal pathways in the rat brain can be probed in situ using high‐resolution three‐dimensional diffusion magnetic resonance imaging and a newly designed tracking approach.
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