Journal ArticleDOI
Psychotomimetic drugs and brain 5-hydroxytryptamine metabolism
TLDR
Both categories of drug influence 5-HT metabolism, and the noted differences with respect to 5-HIAA cannot as yet be accounted for.About:
This article is published in Biochemical Pharmacology.The article was published on 1970-03-01. It has received 97 citations till now. The article focuses on the topics: Psychotomimetic drug & Psilocin.read more
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Comparative Genomics of Listeria Species
Philippe Glaser,Lionel Frangeul,Carmen Buchrieser,Christophe Rusniok,Alexandra Amend,Fernando Baquero,Patrick Berche,H Bloecker,P Brandt,Trinad Chakraborty,Alain Charbit,Farid Chetouani,Elisabeth Couvé,A de Daruvar,Pierre Dehoux,Eugen Domann,Gustavo Domínguez-Bernal,Eric Duchaud,Lionel Durant,Olivier Dussurget,K-D Entian,Hafida Fsihi,F García-del Portillo,P. Garrido,Laurent Gautier,Werner Goebel,Nuria Gomez-Lopez,Torsten Hain,Jörg Hauf,D Jackson,L-M Jones,U Kaerst,Jürgen Kreft,Michael Kuhn,F. Kunst,G Kurapkat,Encarnación Madueño,A Maitournam,J Mata Vicente,E Ng,Hafed Nedjari,G Nordsiek,Susana Novella,B de Pablos,José-Claudio Perez-Diaz,R Purcell,B Remmel,Matthias Rose,T Schlueter,N Simoes,A. Tierrez,José A. Vázquez-Boland,Hamut Voss,Jürgen Wehland,Pascale Cossart +54 more
TL;DR: A large number of predicted genes encoding surface and secreted proteins, transporters, and transcriptional regulators are found, consistent with the ability of both species to adapt to diverse environments.
Journal ArticleDOI
Serotonergic basis of antipsychotic drug effects in schizophrenia
Jeffrey A. Lieberman,Richard B. Mailman,Gary E. Duncan,Lin Sikich,Miranda Chakos,David E. Nichols,John E. Kraus +6 more
TL;DR: The interaction of dopamine and 5-HT systems will be reviewed, and the mechanisms of action of atypical antipsychotic drugs will be evaluated in this context.
Journal ArticleDOI
Stereospecific binding of D-lysergic acid diethylamide (LSD) to brain membranes: relationship to serotonin receptors.
TL;DR: The evidence suggests that D-[3H]LSD binds to post-synaptic serotonin receptors, the only putative neurotransmitter with affinity for the LSD binding site, and psychotropically active alkylindoleamines are also potent displacing agents.
Journal ArticleDOI
Chronic, Multiple Tics of Gilles de la Tourette's Disease: CSF Acid Monoamine Metabolites After Probenecid Administration
TL;DR: Findings suggest an association in Gilles de la Tourette's disease of reduced functioning of inhibitory serotonergic mechanisms and functional dopaminergic overactivity.
Journal ArticleDOI
Hallucinogenic drug interactions with neurotransmitter receptor binding sites in human cortex.
TL;DR: Rank-order differences in affinities are likely to account for the differing effects of these agents in various biochemical and physiological assays.
References
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Methods of Biochemical Analysis
TL;DR: The Radiation Inactivation Method as a Tool to Study Structure-Function Relationships in Proteins Immunoassay with Electrochemical Detection and Theory and Newer Technology Assays for Superoxide Dismutase are studied.
Journal Article
The isolation of nerve endings from brain: An electron microscopic study of cell fragments derived by homogenization and centrifugation
E. G. Gray,Victor P. Whittaker +1 more
Journal Article
Identification and assay of serotonin in brain.
TL;DR: With this method serotonin has been shown to be a normal constituent of brain and may be applied to the measurement of serotonin in other tissues.
Journal ArticleDOI
Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe
TL;DR: An inhibition of neurons containing serotonin after administration of d-lysergic acid diethylamide could account for the decreased metabolism of serotonin produced by this drug.
Journal ArticleDOI
Serotonin: release in the forebrain by stimulation of midbrain raphé
TL;DR: Electrical stimulation of the midbrain raph�, an area in which neuronal perikarya containing serotonin are aggregated, produces an increase in 5-hydroxyindoleacetic acid and a decrease in serotonin in the forebrain, indicating that serotonin inThe brain can be released via a specific neural pathway.