Journal ArticleDOI
Pulmonary atelectasis: a pathogenic perioperative entity.
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TLDR
The authors discuss the effects and implications of atelectasis in the perioperative period and illustrate how preventive measures may impact outcome and the impact of atElectasis and its prevention in acute lung injury.Abstract:
Atelectasis occurs in the dependent parts of the lungs of most patients who are anesthetized. Development of atelectasis is associated with decreased lung compliance, impairment of oxygenation, increased pulmonary vascular resistance, and development of lung injury. The adverse effects of atelectasis persist into the postoperative period and can impact patient recovery. This review article focuses on the causes, nature, and diagnosis of atelectasis. The authors discuss the effects and implications of atelectasis in the perioperative period and illustrate how preventive measures may impact outcome. In addition, they examine the impact of atelectasis and its prevention in acute lung injury.read more
Citations
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Journal ArticleDOI
RNA SequencingThe Twenty-first Century Stethoscope in Pulmonary Medicine
Eliana Lucchinetti,Michael Zaugg +1 more
TL;DR: The data suggested the involvement of the interferon regulatory factor family of transcription factors in endotoxin-exposed atelectasis and YES-associated protein, a transcriptional coactivator of the transcriptional enhanced associate domain transcription factor family, appears to be involved in the loss of pulmonary barrier function of the atelectatic lung.
Journal ArticleDOI
A review of intraoperative lung-protective mechanical ventilation strategy
TL;DR: An overview of the pathophysiology of ventilator-induced lung injury (VILI) on subjects with noninjured lungs, and the intraoperative mechanical ventilation strategies to prevent VILI is provided.
Artigo de Revisão Review Article
R Duarte,Adriana Bastos Carvalho,Diana L. Santos Ferreira,S Saleiro,Ricardo Lima,Márcio Rabelo Mota,Elena Raymundo,Miguel Villar,A. Correia +8 more
TL;DR: In Portugal, tuberculosis incidence has been diminishing although keeping values higher than the rest of the Western Europe, and a new challenge is associated with resistance to drugs, admittedly related to treatment noncompliance or incorrect treatment choice.
Journal ArticleDOI
Influência da posição do dreno pleural na função pulmonar de pacientes submetidos à revascularização do miocárdio
TL;DR: La insercion del drenaje en the region subxifoide altera menos the funcion pulmonar, provoca menos incomodidad and facilita una mejor recuperacion of los parametros respiratorios.
References
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Journal ArticleDOI
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.
Roy G. Brower,Michael A. Matthay,Alan H. Morris,David A. Schoenfeld,B. Taylor Thompson,Arthur P. Wheeler +5 more
TL;DR: In patients with acute lung injury and the acute respiratory distress syndrome, mechanical ventilation with a lower tidal volume than is traditionally used results in decreased mortality and increases the number of days without ventilator use.
Journal ArticleDOI
The acute respiratory distress syndrome
TL;DR: An overview of the definitions, clinical features, and epidemiology of the acute respiratory distress syndrome is provided and advances in the areas of pathogenesis, resolution, and treatment are discussed.
Journal ArticleDOI
Effect of a Protective-Ventilation Strategy on Mortality in the Acute Respiratory Distress Syndrome
Marcelo B. P. Amato,Carmen Silvia Valente Barbas,D Medeiros,R B Magaldi,Guilherme Schettino,Geraldo Lorenzi-Filho,Ronaldo Adib Kairalla,Daniel Deheinzelin,Carlos Munoz,Roselaine Pinheiro de Oliveira,Teresa Yae Takagaki,Carlos Roberto Ribeiro de Carvalho +11 more
TL;DR: As compared with conventional ventilation, the protective strategy was associated with improved survival at 28 days, a higher rate of weaning from mechanical ventilation, and a lower rate of barotrauma in patients with the acute respiratory distress syndrome.
Journal ArticleDOI
Ventilator-induced lung injury: lessons from experimental studies.
Didier Dreyfuss,Georges Saumon +1 more
TL;DR: This paper presents experimental evidence for Increased Vascular Transmural Pressure Evidence for Alterations in Alveolar–Capillary Permeability Contributions of the Static and Dynamic Lung Volume Components to Ventilator-induced Edema High-volume Lung Edema Low Lung Volume Injury.
Journal ArticleDOI
Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial.
V. Marco Ranieri,Peter M. Suter,Cosimo Tortorella,Renato De Tullio,Jean-Michel Dayer,A. Brienza,Francesco Bruno,Arthur S. Slutsky +7 more
TL;DR: Mechanical ventilation can induce a cytokine response that may be attenuated by a strategy to minimize overdistention and recruitment/derecruitment of the lung, and these physiological improvements are associated with improvements in clinical end points.