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Journal ArticleDOI

Pulmonary atelectasis: a pathogenic perioperative entity.

Michelle Duggan, +1 more
- 01 Apr 2005 - 
- Vol. 102, Iss: 4, pp 838-854
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TLDR
The authors discuss the effects and implications of atelectasis in the perioperative period and illustrate how preventive measures may impact outcome and the impact of atElectasis and its prevention in acute lung injury.
Abstract
Atelectasis occurs in the dependent parts of the lungs of most patients who are anesthetized. Development of atelectasis is associated with decreased lung compliance, impairment of oxygenation, increased pulmonary vascular resistance, and development of lung injury. The adverse effects of atelectasis persist into the postoperative period and can impact patient recovery. This review article focuses on the causes, nature, and diagnosis of atelectasis. The authors discuss the effects and implications of atelectasis in the perioperative period and illustrate how preventive measures may impact outcome. In addition, they examine the impact of atelectasis and its prevention in acute lung injury.

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Citations
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References
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Surfactant release in excised rat lung is stimulated by air inflation.

TL;DR: The hypothesis that air inflation to total lung capacity is a major physiological stimulus to release of lung surfactant into the alveolar space is consistent with the hypothesis that the lung lavage process itself also causes the release of Surfactant.
Journal ArticleDOI

Breathing mechanics, dead space and gas exchange in the extremely obese, breathing spontaneously and during anaesthesia with intermittent positive pressure ventilation.

TL;DR: It is concluded that the most probable reason for the relative hypoxaemia is right‐to‐left shunting.
Journal ArticleDOI

Respiratory function and ribcage contribution to ventilation in body positions commonly used during anesthesia

TL;DR: Lung function tests are normally performed in the upright position, whereas anesthesia is usually administered with the patient in the supine position, and occasionally in other postures, so forced vital capacity, forced expiratory volume, and functional residual c are compared.
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Phrenic Nerve Stimulation during Halothane Anesthesia: Effects on Atelectasis

TL;DR: Atelectasis formation during anesthesia may be due to loss of respiratory muscle tone, in particular that of the diaphragm, and this was tested by tensing the diphragm by phrenic nerve stimulation (PNS) and observing the effect on atelectasis.
Journal ArticleDOI

Altered Distribution of Pulmonary Ventilation and Blood Flow Following Induction of Inhalational Anesthesia

TL;DR: An alternative index, the development of CO2 retention at constant alveolar ventilation, more reliably identified patients in whom severe VA/Q inequality developed during inhalational anesthesia.
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