Journal ArticleDOI
Pulmonary atelectasis: a pathogenic perioperative entity.
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TLDR
The authors discuss the effects and implications of atelectasis in the perioperative period and illustrate how preventive measures may impact outcome and the impact of atElectasis and its prevention in acute lung injury.Abstract:
Atelectasis occurs in the dependent parts of the lungs of most patients who are anesthetized. Development of atelectasis is associated with decreased lung compliance, impairment of oxygenation, increased pulmonary vascular resistance, and development of lung injury. The adverse effects of atelectasis persist into the postoperative period and can impact patient recovery. This review article focuses on the causes, nature, and diagnosis of atelectasis. The authors discuss the effects and implications of atelectasis in the perioperative period and illustrate how preventive measures may impact outcome. In addition, they examine the impact of atelectasis and its prevention in acute lung injury.read more
Citations
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Difference between SF6 and N2 Multiple Breath Washout kinetics is due to N2 back diffusion and error in N2 offset.
TL;DR: Significant differences in LCI and FRC measurements using two different gases for MBW are found, which may have significant implications for the future use and interpretation of LCI data in clinical trials and routine clinical care.
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Spinal anaesthesia and non-invasive positive pressure ventilation for hip surgery in an obese patient with advanced chronic obstructive pulmonary disease
C.J. Leech,R. Baba,M. Dhar +2 more
TL;DR: The use of non-invasive positive pressure ventilation combined with spinal anaesthesia to allow the insertion of a dynamic hip screw in an obese patient with advanced chronic obstructive pulmonary disease avoided the hazards of intubation and general anaesthesia.
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Effect of pre-emptive alveolar recruitment strategy before pneumoperitoneum on arterial oxygenation during laparoscopic hysterectomy.
TL;DR: It is concluded that the alveolar recruitment strategy applied before insufflation of the peritoneal cavity may improve oxygenation during laparoscopic hysterectomy.
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Prone equals prone? Impact of positioning techniques on respiratory function in anesthetized and paralyzed healthy children
Britta S. von Ungern-Sternberg,Juerg Hammer,Franz J. Frei,Eva-Maria Jordi Ritz,Andreas Schibler,Thomas O. Erb +5 more
TL;DR: Functional residual capacity and ventilation distribution were similar in the supine and flat prone positions, while these parameters improved significantly in the augmented prone position, suggesting that the technique of prone positioning has major implications for pulmonary function.
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The LIPPSMAck POP (Lung Infection Prevention Post Surgery - Major Abdominal - with Pre-Operative Physiotherapy) trial: study protocol for a multi-centre randomised controlled trial
Ianthe Boden,Ianthe Boden,Laura Browning,Elizabeth H Skinner,Julie Reeve,Julie Reeve,Doa El-Ansary,Iain K Robertson,Iain K Robertson,Linda Denehy +9 more
TL;DR: This trial standardises post-operative assisted ambulation and physiotherapy, measures many known confounders, and includes a post-discharge follow-up of complication rates, functional capacity, and health-related quality of life.
References
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Journal ArticleDOI
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.
Roy G. Brower,Michael A. Matthay,Alan H. Morris,David A. Schoenfeld,B. Taylor Thompson,Arthur P. Wheeler +5 more
TL;DR: In patients with acute lung injury and the acute respiratory distress syndrome, mechanical ventilation with a lower tidal volume than is traditionally used results in decreased mortality and increases the number of days without ventilator use.
Journal ArticleDOI
The acute respiratory distress syndrome
TL;DR: An overview of the definitions, clinical features, and epidemiology of the acute respiratory distress syndrome is provided and advances in the areas of pathogenesis, resolution, and treatment are discussed.
Journal ArticleDOI
Effect of a Protective-Ventilation Strategy on Mortality in the Acute Respiratory Distress Syndrome
Marcelo B. P. Amato,Carmen Silvia Valente Barbas,D Medeiros,R B Magaldi,Guilherme Schettino,Geraldo Lorenzi-Filho,Ronaldo Adib Kairalla,Daniel Deheinzelin,Carlos Munoz,Roselaine Pinheiro de Oliveira,Teresa Yae Takagaki,Carlos Roberto Ribeiro de Carvalho +11 more
TL;DR: As compared with conventional ventilation, the protective strategy was associated with improved survival at 28 days, a higher rate of weaning from mechanical ventilation, and a lower rate of barotrauma in patients with the acute respiratory distress syndrome.
Journal ArticleDOI
Ventilator-induced lung injury: lessons from experimental studies.
Didier Dreyfuss,Georges Saumon +1 more
TL;DR: This paper presents experimental evidence for Increased Vascular Transmural Pressure Evidence for Alterations in Alveolar–Capillary Permeability Contributions of the Static and Dynamic Lung Volume Components to Ventilator-induced Edema High-volume Lung Edema Low Lung Volume Injury.
Journal ArticleDOI
Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial.
V. Marco Ranieri,Peter M. Suter,Cosimo Tortorella,Renato De Tullio,Jean-Michel Dayer,A. Brienza,Francesco Bruno,Arthur S. Slutsky +7 more
TL;DR: Mechanical ventilation can induce a cytokine response that may be attenuated by a strategy to minimize overdistention and recruitment/derecruitment of the lung, and these physiological improvements are associated with improvements in clinical end points.