Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification
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TLDR
In this article, a review of the use of MALDI-TOF in the clinical mycology laboratory is presented, focusing on present and future applications of this versatile analytical tool in the field of bioinformatics.Abstract:
Matrix assisted laser desorption ionization time of flight (MALDI-TOF) is a powerful analytical tool that has revolutionized microbial identification. Routinely used for bacterial identification, MALDI-TOF has recently been applied to both yeast and filamentous fungi, confirming its pivotal role in the rapid and reliable diagnosis of infections. Subspecies-level identification holds an important role in epidemiological investigations aimed at tracing virulent or drug resistant clones. This review focuses on present and future applications of this versatile tool in the clinical mycology laboratory.read more
Citations
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Mass spectrometry in research laboratories and clinical diagnostic: a new era in medical mycology
Hasti Kamali Sarvestani,A Yoosefi Ramandi,Muhammad Ibrahim Getso,Taraneh Razavyoon,Javad Javidnia,Miaad Banay Golrizi,Ali Akbar Saboor-Yaraghi,Saham Ansari +7 more
TL;DR: A review of the most recent research literature that has investigated the applications and usage of MT-MS to the identification of microorganisms, mycotoxins, antifungal susceptibility examination, and mycobiome research can be found in this article .
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