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Raman Spectroscopy—A Prospective Tool in the Life Sciences
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TLDR
The bulk of the review highlights recent applications of Raman spectroscopy, including structural investigations of a hormone receptor, testing the biocompatibility of dental implants, probing soil components and plant tissue alkaloids, and localization of single bacteria.Abstract:
Although the physics of Raman spectroscopy and its application to purely chemical problems is long established, it offers a noninvasive, nondestructive, and water-insensitive probe to problems in the life sciences. Starting from the principles of Raman spectroscopy, its advantages, and methods for signal enhancement, the bulk of the review highlights recent applications. Structural investigations of a hormone receptor, testing the biocompatibility of dental implants, probing soil components and plant tissue alkaloids, and localization of single bacteria are just four problems in which Raman spectroscopy offers a solution or complements existing methods.read more
Citations
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Nanostructures in Biodiagnostics
Nathaniel L. Rosi,Chad A. Mirkin +1 more
TL;DR: Nathaniel L. Rosi focuses on the rational assembly of DNA-modified nanostructures into larger-scale materials and their roles in biodiagnostic screening for nucleic acids.
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Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications
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Can graphene be used as a substrate for Raman enhancement
Xi Ling,Liming Xie,Yuan Fang,Hua Xu,Hao-Li Zhang,Jing Kong,Mildred S. Dresselhaus,Jin Zhang,Zhongfan Liu +8 more
TL;DR: It is observed that the intensities of the Raman signals on monolayer graphene are much stronger than on a SiO(2)/Si substrate, indicating a clear Raman enhancement effect on the surface of monolayers graphene.
Journal ArticleDOI
Identification and quantification of valuable plant substances by IR and Raman spectroscopy
TL;DR: In this article, a review of infrared and Raman spectroscopic methods applied to the analysis of valuable plant substances or quality parameters in horticultural and agricultural crops is presented.
Journal ArticleDOI
SERS: a versatile tool in chemical and biochemical diagnostics
Katharina Konstanze Hering,Dana Cialla,Katrin R. Ackermann,Thomas Dörfer,Robert Möller,Henrik Schneidewind,Roland Mattheis,Wolfgang Fritzsche,Petra Rösch,Jürgen Popp +9 more
TL;DR: In this review, recent developments in SERS spectroscopy are discussed and their impact on different research fields are discussed.
References
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Journal ArticleDOI
Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering
Shuming Nie,Steven R. Emory +1 more
TL;DR: In this article, surface-enhanced Raman scattering was used to detect single molecules and single nanoparticles at room temperature with the use of surface enhanced Raman, and the intrinsic Raman enhancement factors were on the order of 10 14 to 10 15, much larger than the ensemble-averaged values derived from conventional measurements.
Journal ArticleDOI
Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS)
Katrin Kneipp,Katrin Kneipp,Yang Wang,Yang Wang,Harald Kneipp,Harald Kneipp,Lev T. Perelman,Lev T. Perelman,Irving Itzkan,Irving Itzkan,Ramachandra R. Dasari,Ramachandra R. Dasari,Michael S. Feld,Michael S. Feld +13 more
TL;DR: In this article, the first observation of single molecule Raman scattering was made using a single crystal violet molecule in aqueous colloidal silver solution using one second collection time and about $2.
Journal ArticleDOI
Raman spectra of pyridine adsorbed at a silver electrode
TL;DR: In this article, Ramaman spectroscopy has been employed for the first time to study the role of adsorption at electrodes, and it has been possible to distinguish two types of pyridine adaption at a silver electrode.
Journal ArticleDOI
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
Krzysztof Palczewski,Takashi Kumasaka,Tetsuya Hori,Craig A. Behnke,H. Motoshima,Brian A. Fox,I. Le Trong,David C. Teller,Tetsuji Okada,Ronald E. Stenkamp,Masaki Yamamoto,Masashi Miyano +11 more
TL;DR: This article determined the structure of rhodopsin from diffraction data extending to 2.8 angstroms resolution and found that the highly organized structure in the extracellular region, including a conserved disulfide bridge, forms a basis for the arrangement of the sevenhelix transmembrane motif.
Journal ArticleDOI
Ultrasensitive Chemical Analysis by Raman Spectroscopy
TL;DR: The spontaneous Raman effect, in the following simply called Raman scattering, is focused on, which can be applied noninvasively under ambient conditions in almost every environment and has special importance for ultrasensitive Raman spectroscopy at the singlemolecule level.
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