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Journal ArticleDOI

Rate and rhythm control have comparable effects on mortality and stroke in atrial fibrillation but better data are needed.

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TLDR
A systematic review and meta-analysis of tabular data addresses the benefits and risks of adding rhythm control to rate control therapy, and considers the preferential method.
Abstract
Commentary on : Al-Khatib SM, Allen LaPointe NM, Chatterjee R, et al. Rate- and rhythm-control therapies in patients with atrial fibrillation: a systematic review. Ann Intern Med 2014;160:760–73.[OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Atrial fibrillation (AF) represents a large and growing burden on cardiovascular healthcare and leads to a substantial impact on quality-of-life, increased cardiovascular events and a doubling of hospitalisation and death rates.1 Unlike many other cardiac conditions, the evidence base for treatment in AF remains patchy with clear gaps relating to a number of clinically important management strategies. Current practice involves three major elements: anticoagulation to prevent stroke or systemic embolism, medications to control heart rate and a decision on whether to restore and maintain sinus rhythm. This systematic review and meta-analysis of tabular data addresses the benefits and risks of adding rhythm control to rate control therapy, considers the preferential method … [1]: {openurl}?query=rft.jtitle%253DAnn%2BIntern%2BMed%26rft.volume%253D160%26rft.spage%253D760%26rft_id%253Dinfo%253Adoi%252F10.7326%252FM13-1467%26rft_id%253Dinfo%253Apmid%252F24887617%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.7326/M13-1467&link_type=DOI [3]: /lookup/external-ref?access_num=24887617&link_type=MED&atom=%2Febmed%2F19%2F6%2F222.atom [4]: /lookup/external-ref?access_num=000337348700003&link_type=ISI

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Journal ArticleDOI

A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference.

Paulus Kirchhof, +72 more
- 01 Jan 2016 - 
TL;DR: This report reports the outcome of the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference in Nice, France, with a focus on learning from 'neighbours' to improve AF care, and a list of priorities for research in AF patients.
References
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Journal ArticleDOI

Guidelines for the management of atrial fibrillation The Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC)

TL;DR: Estimates of expected health outcomes for larger societies are included, where data exist, and the level of evidence and the strength of recommendation of particular treatment options are weighed and graded according to pre-defined scales.
Journal ArticleDOI

Guidelines for the management of atrial fibrillation

TL;DR: Guidelines summarize and evaluate all currently available evidence on a particular issue with the aim of assisting physicians in selecting the best management strategy for an individual patient suffering from a given condition, taking into account the impact on outcome, as well as the risk–benefit ratio of particular diagnostic or therapeutic means.
Journal ArticleDOI

Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060

TL;DR: The number of adults 55 years and over with AF in the European Union will more than double from 2010 to 2060, and this increasing number of individuals with AF may have major public health implications.
Journal ArticleDOI

When can odds ratios mislead

TL;DR: Odds ratios are a common measure of the size of an effect and may be reported in case-control studies, cohort studies, or clinical trials, and are also used to report the findings from systematic reviews and meta-analyses.
Journal ArticleDOI

Treatment of Atrial Fibrillation With Antiarrhythmic Drugs or Radiofrequency Ablation Two Systematic Literature Reviews and Meta-Analyses

TL;DR: In this article, the relative safety and efficacy of radiofrequency catheter ablation (RFA) for atrial fibrillation were evaluated using a randomized clinical trial, and the results showed that RFA is safe and effective.
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