Journal ArticleDOI
Recent advances in acyl radical enabled reactions between aldehydes and alkenes
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TLDR
A summary of the state of the art in this field with a specific emphasis on the working models and corresponding mechanisms is provided in this paper, where the discussion is divided according to the kind of alkenes and reaction type.About:
This article is published in Chemical Communications.The article was published on 2021-06-22. It has received 23 citations till now.read more
Citations
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NHC and visible light-mediated photoredox co-catalyzed 1,4-sulfonylacylation of 1,3-enynes for tetrasubstituted allenyl ketones
TL;DR: NHC and visible light-mediated photoredox co-catalyzed radical 1,4-sulfonylacylation of 1,3-enynes is described, providing structurally diversified valuable tetrasubstituted allenyl ketones and highly selective cross-coupling of an acyl radical with an alkyl radical for efficient construction of C–C bonds.
Journal ArticleDOI
Efficient Access to β-Amino Acid Ester/β-Amino Ketone Derivatives via Photocatalytic Radical Alkoxycabonylimidation/ Carbonylimidation of Alkenes
TL;DR: In this article , a photocatalytic protocol for the synthesis of β-amino acid ester and βamino ketone derivatives is developed by using simple and easy-to-synthesize oxime oxalate and oxime phenylglyoxylate as difunctionalization reagents.
Journal ArticleDOI
Iron-Catalyzed Dearomatization of Biaryl Ynones with Aldehydes via Double C-H Functionalization in Eco-Benign Solvents: Highly Atom-Economical Synthesis of Acylated Spiro[5.5]trienones.
Dong Xia,Xin-Fang Duan +1 more
TL;DR: In this paper, an unprecendented dearomatization of biaryl ynones with aldehydes via double C-H functionalization was reported, where a regiospecific remote unactivated para-C-H function was used to efficiently furnishes acylated spiro[5.5]trienones.
Journal ArticleDOI
Thiazole-5-carbaldehyde Synthesis by Cascade Annulation of Enaminones and KSCN with Dess-Martin Periodinane Reagent.
TL;DR: DMP plays dual roles in mediating the free radical thiocyanation and inducing the unconventional selective thiazole-5-carbaldehyde formation by masking the in situ generated formyl group during the reaction process.
References
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Journal ArticleDOI
Recent Advances on the Photo-Induced Reactions of Acyl Radical
Journal ArticleDOI
Heat- or light-induced acylarylation of unactivated alkenes towards 3-(α-acyl) indolines
Yanni Li,Fengyuan Ying,Tingfeng Fu,Ruihan Yang,Ying Dong,Liqing Lin,Liqing Lin,Yinghui Han,Yinghui Han,Deqiang Liang,Xianhao Long +10 more
TL;DR: A heat- or photoredox/iron dual catalysis-enabled dehydrogenative acylarylation of N-allyl anilines leading to 2-substituted 3-(α-acyl) indolines with a quaternary stereogenic center is presented, with unactivated alkenic bonds as radical acceptors and simple aldehydes as radical precursors.
Journal ArticleDOI
Oxidative cross-coupling processes inspired by the Chan-Lam reaction.
TL;DR: This feature article describes the discovery and application of Cu-catalyzed oxidative coupling reactions of activated methylene derivatives or carboxylic acids with nucleophiles including aryl boronic esters and amines.
Journal ArticleDOI
A General Approach to Intermolecular Olefin Hydroacylation through Light-Induced HAT Initiation: An Efficient Synthesis of Long-Chain Aliphatic Ketones and Functionalized Fatty Acids.
Subhasis Paul,Joyram Guin +1 more
TL;DR: In this paper, an operationally simple, environmentally benign, and effective method for intermolecular radical hydroacylation of unactivated substrates employing photo-induced hydrogen atom transfer (HAT) initiation is described.
Journal ArticleDOI
Radical Tandem Bicyclization Triggered by the α-Position of α,β-Unsaturated Ketones Bearing Nonterminal 1,6-Enynes: Synthesis of the 5H-Benzo[a]fluoren-5-one Skeleton.
You Zhou,Peng Zhao,Xiao-Xiao Yu,Xiao Geng,Can Wang,Chun Huang,Hai Yang,Zhi-Yong Zhao,An-Xin Wu +8 more
TL;DR: A novel method for the synthesis of 5H-benzo[a]fluoren-5-one from inactive nonterminal 1,6-alkynes through a free radical tandem bicyclization process has been established and achieved a continuous cyclization triggered rarely by the α-position of α,β-unsaturated ketones.
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