Journal ArticleDOI
Recent advances in acyl radical enabled reactions between aldehydes and alkenes
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TLDR
A summary of the state of the art in this field with a specific emphasis on the working models and corresponding mechanisms is provided in this paper, where the discussion is divided according to the kind of alkenes and reaction type.About:
This article is published in Chemical Communications.The article was published on 2021-06-22. It has received 23 citations till now.read more
Citations
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NHC and visible light-mediated photoredox co-catalyzed 1,4-sulfonylacylation of 1,3-enynes for tetrasubstituted allenyl ketones
TL;DR: NHC and visible light-mediated photoredox co-catalyzed radical 1,4-sulfonylacylation of 1,3-enynes is described, providing structurally diversified valuable tetrasubstituted allenyl ketones and highly selective cross-coupling of an acyl radical with an alkyl radical for efficient construction of C–C bonds.
Journal ArticleDOI
Efficient Access to β-Amino Acid Ester/β-Amino Ketone Derivatives via Photocatalytic Radical Alkoxycabonylimidation/ Carbonylimidation of Alkenes
TL;DR: In this article , a photocatalytic protocol for the synthesis of β-amino acid ester and βamino ketone derivatives is developed by using simple and easy-to-synthesize oxime oxalate and oxime phenylglyoxylate as difunctionalization reagents.
Journal ArticleDOI
Iron-Catalyzed Dearomatization of Biaryl Ynones with Aldehydes via Double C-H Functionalization in Eco-Benign Solvents: Highly Atom-Economical Synthesis of Acylated Spiro[5.5]trienones.
Dong Xia,Xin-Fang Duan +1 more
TL;DR: In this paper, an unprecendented dearomatization of biaryl ynones with aldehydes via double C-H functionalization was reported, where a regiospecific remote unactivated para-C-H function was used to efficiently furnishes acylated spiro[5.5]trienones.
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Thiazole-5-carbaldehyde Synthesis by Cascade Annulation of Enaminones and KSCN with Dess-Martin Periodinane Reagent.
TL;DR: DMP plays dual roles in mediating the free radical thiocyanation and inducing the unconventional selective thiazole-5-carbaldehyde formation by masking the in situ generated formyl group during the reaction process.
References
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Journal ArticleDOI
Asymmetric hydrofunctionalization of minimally functionalized alkenes via earth abundant transition metal catalysis
Jianhui Chen,Zhan Lu +1 more
TL;DR: In this article, the authors summarized the advances of the highly enantioselective (≥90% ee) hydrofunctionalization reactions of minimally functionalized alkenes using earth-abundant transition metals (iron, cobalt, nickel, copper, titanium and zirconium) as catalysts.
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Recent advances in the sulfonylation of alkenes with the insertion of sulfur dioxide via radical reactions.
TL;DR: The sulfur dioxide surrogate of DABCO·(SO2)2 or inorganic sulfites is used in the transformation through a radical process and the asymmetric vicinal difunctionalization of alkenes with the insertion of sulfur dioxide will be developed rapidly in the near future.
Journal ArticleDOI
Difunctionalization of Alkenes Involving Metal Migration.
TL;DR: The direct difunctionalization of alkenes, a cheap and abundant feedstock, represents one of the most attractive strategies to greatly increase molecular complexity in synthetic organic chemistry and significantly renovates the bond disconnections available in modern organic synthesis.
Journal ArticleDOI
A general deoxygenation approach for synthesis of ketones from aromatic carboxylic acids and alkenes.
TL;DR: A deoxygenative coupling of carboxylic acids and alkenes enabled by photoredox catalysis is shown and a wide scope of products are reported, including bioactive and macrocyclic ketones.
Journal ArticleDOI
Deoxygenative Deuteration of Carboxylic Acids with D2O
TL;DR: A general, practical, and scalable means of preparing deuterated aldehydes from aromatic and aliphatic carboxylic acids with D2 O as an inexpensive deuterium source is reported.
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