Recombinant Surface Proteomics as a Tool to Analyze Humoral Immune Responses in Bovines Infected by Mycoplasma mycoides Subsp. mycoides Small Colony Type
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TLDR
A toolbox with recombinant proteins and a flexible suspension array assay that allows multiplex analysis of humoral immune responses to M. mycoides SC has been created.About:
This article is published in Molecular & Cellular Proteomics.The article was published on 2009-11-01 and is currently open access. It has received 23 citations till now. The article focuses on the topics: Mycoplasma mycoides.read more
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Autoantibody Profiling in Multiple Sclerosis Using Arrays of Human Protein Fragments
Burcu Ayoglu,Anna Häggmark,Mohsen Khademi,Tomas Olsson,Mathias Uhlén,Jochen M. Schwenk,Peter Nilsson +6 more
TL;DR: Using protein fragments and complementary high-throughput protein array platforms facilitated an alternative route to discovery and verification of potentially disease-associated autoimmunity signatures, that are now proposed as additional antigens for large-scale validation studies across multiple sclerosis biobanks.
Journal ArticleDOI
Development of an improved vaccine for contagious bovine pleuropneumonia: an African perspective on challenges and proposed actions
TL;DR: It is suggested that different vaccine development approaches are followed in parallel and basic immunology studies and systematic OMICs studies will be necessary in order to identify the protective arms of immunity and to shed more light on the pathogenicity mechanisms in CBPP.
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Plasma profiling reveals human fibulin-1 as candidate marker for renal impairment.
Maja Neiman,Jesper J. Hedberg,Pierre Dönnes,Ina Schuppe-Koistinen,Stephan Hanschke,Ralf Schindler,Mathias Uhlén,Jochen M. Schwenk,Peter Nilsson +8 more
TL;DR: It is suggested that plasma levels of fibulin-1 could serve as a potential indicator to monitor kidney malfunction or kidney damage.
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A Lateral Flow Protein Microarray for Rapid and Sensitive Antibody Assays
TL;DR: It is proposed that the presented framework could find use in convenient and cost-efficient quality control of antibody production, as well as in providing a platform for multiplexed affinity-based assays in low-resource or mobile settings.
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Specific Evolution of F1-Like ATPases in Mycoplasmas
Laure Béven,Claire Charenton,Alain Dautant,Guillaume Bouyssou,Fabien Labroussaa,Anna Sköllermo,Anja Persson,Alain Blanchard,Pascal Sirand-Pugnet +8 more
TL;DR: A model, in which the F1-like structure is associated with a hypothetical X0 sector located in the membrane of mycoplasma cells, is proposed, which suggests that Type 3 ATPase clusters may spread to other phylogenetic groups by horizontal gene transfer between my coplasmas in the same host, based on phylogeny and genomic context.
References
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