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Journal ArticleDOI

Relationship of Helicobacter pylori to serum pepsinogens in an asymptomatic Japanese population.

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TLDR
The apparent decrease in prevalence of H. pylori accompanying the Westernization of Japan may eventually be accompanied by a reduction in the frequency of atrophic gastritis, the precursor lesion of the epidemic form of gastric carcinoma, and ultimately result in a decrease in the incidence of gastRIC carcinoma in Japan.
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This article is published in Gastroenterology.The article was published on 1992-03-01. It has received 622 citations till now. The article focuses on the topics: Atrophic gastritis & Helicobacter pylori.

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Citations
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Epidemiology of gastric cancer

TL;DR: Diverging trends in the incidence of gastric cancer by tumor location suggest that they may represent two diseases with different etiologies, and strategies for primary prevention are discussed.
Journal Article

Epidemiology of gastric cancer.

TL;DR: The incidence of gastric cancer varies widely by country and population, with higher rates among the lower socioeconomic groups as discussed by the authors, although rates have generally decreased, there has been a dramatic increase in the incidence of Gastric cancer in the cardia.
Journal Article

The prevalence of Helicobacter pylori infection in different countries.

TL;DR: The prevalence of Helicobacter pylori infection in a community is related to three factors: firstly, the rate of acquisition of infection with H.pylori--that is, incidence; secondly, the rates of loss of the infection; and thirdly,The prolonged persistence of the bacterium in the gastroduodenal mucosa between infection and eradication.
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Importance of childhood socioeconomic status on the current prevalence of Helicobacter pylori infection.

TL;DR: The increased prevalence of H pylori in black and Hispanic people seems to be related to low socioeconomic status in childhood, which is consistent with the suggestion that childhood is a period of major risk for Hpylori infection.
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Guidelines for the management of Helicobacter pylori infection in Japan: 2009 revised edition.

TL;DR: The committee of the Japanese Society for Helicobacter Research has revised the guidelines for diagnosis and treatment of H. pylori infection in Japan, finding the relationship between H.pylori and gastric cancer has been demonstrated more clearly.
References
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Journal ArticleDOI

Epidemiology of Helicobacter pylori in an asymptomatic population in the United States: Effect of age, race, and socioeconomic status

TL;DR: The prevalence of H. pylori infection among 485 healthy asymptomatic volunteers between the ages of 15 and 80 residing in the Houston metropolitan area was investigated and it was found that having pets was associated with a lower frequency, but this was highly associated with higher socioeconomic status.
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Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons

TL;DR: In this paper, the authors estimated the prevalences of Helicobacter pylori infection and histologic gastritis in 113 asymptomatic persons, using endoscopic biopsy of the gastric antrum and corpus.
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Campylobacter pylori and peptic ulcer disease

TL;DR: The data is reviewed and mechanisms that implicate C. pylori as an important factor in the pathogenesis of peptic ulcer disease are proposed and the therapeutic implications are considered.
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Seroepidemiology of Campylobacter pylori infection in various populations.

TL;DR: The epidemiological data available on peptic ulcer disease in developing countries compared with developed countries led to the speculation that infection with C. pylori is not a sufficient condition to develop this disease.
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Relationships among serum pepsinogen I, serum pepsinogen II, and gastric mucosal histology. A study in relatives of patients with pernicious anemia.

TL;DR: The results indicate that increasing severity of gastritis is associated with nonparallel alterations in serum levels of pepsinogen I and pepinogen II, and that these changes lead to a progressive decrease in the peps inogen I to pepsInogen II ratio, which is predictive of the histologic status of the gastric mucosa.
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