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Journal ArticleDOI

Revision of vagal nerve stimulation (VNS) electrodes: review and report on use of ultra-sharp monopolar tip

TLDR
VNS revision is normally performed in cases of device malfunction or infection and can be safely performed using a combination of ultra-sharp monopolar coagulation and sharp dissection using the use of the ultra- sharp monopolar tip for safe dissection and removal of the electrode from the vagus nerve.
Abstract
As a result of the increasingly popularity of vagal nerve stimulation (VNS) for intractable seizures, neurosurgeons not uncommonly encounter cases which require electrode revision. We examine our experience of VNS revision and reports the use of the ultra-sharp monopolar tip for safe dissection and removal of the electrode from the vagus nerve. A retrospective review was performed from January 2000 to Dec 2009 reviewed eight cases of VNS revision. The indications for VNS revision were device malfunction manifesting with increased seizures or increased impedance of the device and infection. The time from initial VNS implantation to revision ranged from 6 to 108 months (mean: 38 months). The entire VNS electrode system, was removed in seven cases and the helical coils were left in-situ in one case who did not derive any benefit from VNS and it was deemed unnecessary to subject the patient to the additional risk of vagal nerve injury. One case had dislodgement of the lower two coils and three cases had dense scarring to the vagus nerve causing high impedance and malfunction. The other three cases demonstrated no fibrotic scar tissue between the helical coils and the vagus nerve. Four cases had replacement of new VNS system but the case of infected VNS stimulator was not replaced as there was no benefit from the device. VNS revision is normally performed in cases of device malfunction or infection and can be safely performed using a combination of ultra-sharp monopolar coagulation and sharp dissection.

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Journal ArticleDOI

Vagus nerve stimulation: Surgical technique of implantation and revision and related morbidity.

TL;DR: Indications for vagus nerve stimulation (VNS) therapy include focal, multifocal epilepsy, drop attacks (tonic/atonic seizures), Lennox‐Gastaut syndrome, tuberous sclerosis complex (TSC)–related multifocal seizures, and unsuccessful resective surgery.
Journal ArticleDOI

Complications and safety of vagus nerve stimulation: 25 years of experience at a single center

TL;DR: VNS implantation is a relatively safe procedure, but it still involves certain risks, and it is important to include repeated surgeries such as battery and lead replacements, given that complications also may occur with these surgeries.
Journal ArticleDOI

Vagus Nerve Stimulation (VNS) and Other Augmentation Strategies for Therapy-Resistant Depression (TRD): Review of the Evidence and Clinical Advice for Use

TL;DR: This mini-review provides a comprehensive overview of augmentation pharmacotherapy and neurostimulation-based treatment strategies, with a special focus on VNS in TRD, and provides practical clinical advice for how to select TRD patients for add-on neuro Stimulation treatment strategies.
Journal ArticleDOI

Vagus nerve stimulation lead removal or replacement: surgical technique, institutional experience, and literature overview

TL;DR: Complete removal or replacement of the VNS system including lead and coils is feasible and safe and further research and longer follow-up are needed to assess whether lead replacement may affect VNS effectiveness.
Journal ArticleDOI

Biomechanical and functional variation in rat sciatic nerve following cuff electrode implantation

TL;DR: Tethering resulting from cuff implantation resulted in altered nerve strain and a complex biomechanical environment during joint movement, which emphasizes the importance of the mechanical interface between peripheral nerves and their devices on neurophysiological performance.
References
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Journal ArticleDOI

Prevention of Intractable Partial Seizures by Intermittent Vagal Stimulation in Humans: Preliminary Results

TL;DR: Vagal stimulation represents a novel approach for seizure control in patients who have intractable epilepsy, but additional studies are needed to clarify the efficacy and safety of the procedure and to define selection criteria for patients.
Journal ArticleDOI

Treatment of epilepsy by stimulation of the vagus nerve

TL;DR: Most patients tolerated the device and stimulation well, and two patients have been seizure-free for over 1 year and some cases of medically refractory partial seizures are improved by vagal stimulation.
Journal ArticleDOI

An institutional experience with cervical vagus nerve trunk stimulation for medically refractory epilepsy: rationale, technique, and outcome.

TL;DR: In the experience, vagus nerve stimulation has proven to be a safe, feasible, and potentially effective method of reducing seizures in select patient populations, however, the elements of strict definition for the application of the method require further study.
Journal ArticleDOI

Efficacy and safety of vagus nerve stimulation in patients with complex partial seizures.

TL;DR: A clinical trial of chronic intermittent vagal stimulation in five patients suggests that the procedure may be safe and effective as adjunctive treatment of medically intractable seizures of partial onset.
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