Journal ArticleDOI
Rice (Oryza sativa L.) inhibits growth and induces differentiation of human leukemic U937 cells through activation of peripheral blood mononuclear cells
TLDR
It is demonstrated that MT9 and BT9 can inhibit growth and induce differentiation of leukemic U937 cells through activation of human peripheral blood MNC in vitro, which could be biological response modifiers for augmenting anti-leukemia immunity.About:
This article is published in Food and Chemical Toxicology.The article was published on 2006-10-01. It has received 33 citations till now. The article focuses on the topics: Peripheral blood mononuclear cell & U937 cell.read more
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Reclamation of chitinous materials by bromelain for the preparation of antitumor and antifungal materials
TL;DR: The main purpose of this research was to investigate the antitumor and antimicrobial activities of the chitooligosaccharides containing hydrolyzates obtained from the hydrolysis of chitinous materials (such as chitin, chitosan, and squid pen) by bromelain.
Journal ArticleDOI
Ethnopharmacological analysis of medicinal plants and animals used in the treatment and management of pain in Mauritius
TL;DR: The present ethnopharmacological study revealed a panoply of TM to be in common use for pain management and treatment in Mauritius and documented for the first time medicinal plants and animal species with potential analgesic and/or anti-nociceptive properties.
Journal ArticleDOI
Rice - not just a staple food: A comprehensive review on its phytochemicals and therapeutic potential
TL;DR: In this article, the authors summarized the available literature on health-promoting and therapeutic activity of rice and rice biomolecules, and discussed the possible molecular mechanisms of action of the rice/rice part/biomolecules.
Journal ArticleDOI
MGN-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherapeutic agent, daunorubicin.
Sastry Gollapudi,Mamdooh Ghoneum +1 more
TL;DR: The data demonstrate that MGN-3 is an effective chemo-sensitizer and may represent a potential novel adjuvant for the treatment of breast cancer.
Journal ArticleDOI
Cereal-Derived Arabinoxylans as Biological Response Modifiers: Extraction, Molecular Features, and Immune-Stimulating Properties
TL;DR: Current research on the immune-enhancing activities of arabinoxylans and other cereal polysaccharides in relation to their structural heterogeneity is discussed.
References
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Journal ArticleDOI
Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients
Zhi-Xiang Shen,Guo-Qiang Chen,Jian-Hua Ni,Xiu-Shong Li,Shu-Min Xiong,Qian-Yao Qiu,Jun Zhu,Wei Tang,Guan-Lin Sun,Kan-Qi Yang,Yu Chen,Li Zhou,Zhi-Wen Fang,Yan-Ting Wang,Jun Ma,Peng Zhang,Ting-Dong Zhang,Sai-Juan Chen,Zhu Chen,Zhen-Yi Wang +19 more
TL;DR: As2O3 treatment is an effective and relatively safe drug in APL patients refractory to ATRA and conventional chemotherapy, and Pharmacokinetic studies showed that after a peak level of 5.54 micromol/L, plasma arsenic was rapidly eliminated, and the continuous administration of As2O2 did not alter its pharmacokinetic behaviors.
Journal ArticleDOI
Quantitative Nitroblue Tetrazolium Test in Chronic Granulomatous Disease
TL;DR: Chronic granulomatous disease is an X-linked defect in the killing of certain bacteria by peripheral blood granulocytes and may be detected with the nitroblue tetrazolium (NBT) test.
Journal ArticleDOI
The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes
TL;DR: Antibody‐neutralization studies further revealed that the anti‐tumor cytokines in the PSG‐MNC‐CM were mainly of TNF‐α and IFN‐γ, and these 2 cytokines acted synergistically on the inhibition of leukemic‐cell growth.
Journal Article
Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy.
Monte Fisher,Li-Xi Yang +1 more
TL;DR: PSK has been shown to have antioxidant capacity which may allow it to play a role as a normal tissue chemo- and radio-protector when used in combination with adjuvant or definitive chemotherapy and/or radiotherapy in the treatment of cancer, while it may also enable it to defend the host from oxidative stress.
Journal ArticleDOI
Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells.
TL;DR: Antibody neutralization studies revealed that the tumoricidal and differentiating effects of PSCS-MNC-CM were mainly derived from the elevated cytokines, especially IFN-gamma and TNF-alpha, which acted synergistically on inhibiting cell growth and inducing differentiation of the target U937 cells.
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Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells.
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Yue-Yawn Chen,Hung-Min Chang +1 more