Journal ArticleDOI
Role of environmental estrogens in the deterioration of male factor fertility.
TLDR
Ejaculate volume, sperm count, progressive motility, normal morphology, and fertilizing capacity were significantly lower in infertile men compared with controls, and PCBs and PEs may be instrumental in the deterioration of semen quality.About:
This article is published in Fertility and Sterility.The article was published on 2002-12-01. It has received 237 citations till now. The article focuses on the topics: Semen quality & Sperm.read more
Citations
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Journal ArticleDOI
Men at risk: occupation and male infertility☆
TL;DR: There is accumulating evidence that workplace exposure to toxic substances contributes to male infertility, and men suffering from infertility problems may do well to look at their occupations, where exposure to certain substances may be a contributory factor.
Journal ArticleDOI
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
Andrea C. Gore,Vesna A. Chappell,Suzanne E. Fenton,Jodi A. Flaws,Angel Nadal,Gail S. Prins,Jorma Toppari,R. T. Zoeller +7 more
TL;DR: A much more complete understanding of the endocrine principles by which EDCs act, including nonmonotonic dose-responses, low-dose effects, and developmental vulnerability, can be much better translated to human health.
Journal ArticleDOI
Phthalates and human health
Russ Hauser,Antonia M. Calafat +1 more
TL;DR: The uses and metabolism of phthalates, and the studies on health effects ofphthalates in human populations published between 1973 and June 2005 are reviewed.
Journal ArticleDOI
Phthalates and other additives in plastics: human exposure and associated health outcomes
TL;DR: There is a great need for more human studies of adverse health effects associated with plastic additives, and recent advances in the measurement of exposure biomarkers hold much promise in improving the epidemiological data, but their utility must be understood to facilitate appropriate study design.
Journal ArticleDOI
Reproductive and Developmental Toxicity of Phthalates
Jan Ludvig Lyche,Arno C. Gutleb,Åke Bergman,Gunnar Sundstøl Eriksen,Albertinka J. Murk,Erik Ropstad,Margaret Saunders,Janneche Utne Skaare +7 more
TL;DR: It is concluded that it is important to improve the knowledge of toxic interactions among the different chemicals and to develop measures for combined exposure to various groups of phthalates.
References
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Journal ArticleDOI
Developmental effects of endocrine-disrupting chemicals in wildlife and humans.
TL;DR: Mechanisms underlying the disruption of the development of vital systems, such as the endocrine, reproductive, and immune systems, are discussed with reference to wildlife, laboratory animals, and humans.
Journal ArticleDOI
Evidence for decreasing quality of semen during past 50 years.
TL;DR: There has been a genuine decline in semen quality over the past 50 years, and as male fertility is to some extent correlated with sperm count the results may reflect an overall reduction in male fertility.
Laboratory manual for the examination of human semen and semen-cervical mucus interaction.
TL;DR: This laboratory manual consists of 2 sections which describe methods of examination of human semen and semen-cervical mucus interaction in order to standardize procedures and facilitate evaluation and comparison of research reports.
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Development of an assay to assess the functional integrity of the human sperm membrane and its relationship to other semen characteristics
TL;DR: The hypoosmotic swelling technique to evaluate the functional integrity of the sperm membrane appears to give high repeatability and accuracy and is closely correlated to the in-vitro fertilizing ability of spermatozoa.
Journal ArticleDOI
Male reproductive health and environmental xenoestrogens
Jorma Toppari,John Chr. Larsen,Peter Christiansen,Aleksander Giwercman,Philippe Grandjean,Louis J. Guillette,Bernard Jégou,Tina Kold Jensen,Pierre Jouannet,Niels Keiding,Henrik Leffers,John A. McLachlan,Otto A. Meyer,Jørn Müller,E. Rajpert-De Meyts,Thomas H. Scheike,Richard M. Sharpe,John P. Sumpter,Niels E. Skakkebæk +18 more
TL;DR: The growing number of reports demonstrating that common environmental contaminants and natural factors possess estrogenic activity presents the working hypothesis that the adverse trends in male reproductive health may be, at least in part, associated with exposure to estrogenic or other hormonally active environmental chemicals during fetal and childhood development.