Journal ArticleDOI
Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial Reliability and Validity Data
Joan Kaufman,Boris Birmaher,David A. Brent,Uma Rao,Uma Rao,Cynthia Flynn,Cynthia Flynn,Paula Moreci,Douglas E. Williamson,Neal D. Ryan +9 more
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TLDR
Results suggest the K-SADS-PL generates reliable and valid child psychiatric diagnoses.Abstract:
Objective To describe the psychometric properties of the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL) interview, which surveys additional disorders not assessed in prior K-SADS, contains improved probes and anchor points, includes diagnosis-specific impairment ratings, generates DSM-III-R and DSM-IV diagnoses, and divides symptoms surveyed into a screening interview and five diagnostic supplements. Method Subjects were 55 psychiatric outpatients and 11 normal controls (aged 7 through 17 years). Both parents and children were used as informants. Concurrent validity of the screen criteria and the K-SADS-PL diagnoses was assessed against standard self-report scales. Interrater ( n = 15) and test-retest ( n = 20) reliability data were also collected (mean retest interval: 18 days; range: 2 to 38 days). Results Rating scale data support the concurrent validity of screens and K-SADS-PL diagnoses. Interrater agreement in scoring screens and diagnoses was high (range: 93% to 100%). Test-retest reliability κ coefficients were in the excellent range for present and/or lifetime diagnoses of major depression, any bipolar, generalized anxiety, conduct, and oppositional defiant disorder (.77 to 1.00) and in the good range for present diagnoses of posttraumatic stress disorder and attention-deficit hyperactivity disorder (.63 to .67). Conclusion Results suggest the K-SADS-PL generates reliable and valid child psychiatric diagnoses. J. Am. Acad. Child Adolesc. Psychiatry , 1997, 36(7): 980–988.read more
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Eating habits and attitudes among 10-year-old children of mothers with eating disorders: longitudinal study.
Alan Stein,H Woolley,Sandra Cooper,Jonathan Winterbottom,Christopher G. Fairburn,Mario Cortina-Borja +5 more
TL;DR: The children of mothers with eating disorders manifested disturbed eating habits and attitudes compared with controls, and may be at heightened risk of developing frank eating disorder psychopathology.
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Preliminary Findings Regarding Proinflammatory Markers and Brain-Derived Neurotrophic Factor Among Adolescents with Bipolar Spectrum Disorders
Benjamin I. Goldstein,Katelyn Collinger,Francis Lotrich,Anna L. Marsland,MaryKay Gill,David Axelson,Boris Birmaher +6 more
TL;DR: In this paper, the authors examined serum interleukin-6, high-sensitivity C-reactive protein (hsCRP), and BDNF among 30 bipolar disorder adolescents.
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Reduced antioxidant defense in early onset first-episode psychosis: a case-control study
Juan Antonio Mico,M.O. Rojas-Corrales,Juan Gibert-Rahola,Mara Parellada,Dolores Moreno,David Fraguas,Montserrat Graell,Javier Gil,Jon Irazusta,Josefina Castro-Fornieles,Cesar Soutullo,Celso Arango,Soraya Otero,Ana Navarro,Inmaculada Baeza,Mónica Martínez-Cengotitabengoa,Ana González-Pinto +16 more
TL;DR: This study shows a decrease in the antioxidant defense system in early onset first episode psychotic patients, and glutathione deficit seems to be implicated in psychosis, and may be an important indirect biomarker of oxidative stress in early-onset schizophrenia.
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Actigraphic and parental reports of sleep difficulties in children with attention-deficit/hyperactivity disorder.
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Preliminary data suggesting the efficacy of attention training for school-aged children with ADHD
TL;DR: Results showed significant treatment effects for parent and clinician ratings of ADHD symptoms, child self-report of ability to focus, and parent ratings of executive functioning, and no treatment effects were observed on other neuropsychological outcomes.
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