Journal ArticleDOI
Sonofragmentation of Molecular Crystals
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TLDR
Direct particle-shock wave interactions are indicated as the primary mechanism of sonofragmentation of molecular crystals.Abstract:
Possible mechanisms for the breakage of molecular crystals under high-intensity ultrasound were investigated using acetylsalicylic acid (aspirin) crystals as a model compound for active pharmaceutical ingredients. Surprisingly, kinetics experiments ruled out particle–particle collisions as a viable mechanism for sonofragmentation. Two other possible mechanisms (particle–horn and particle–wall collisions) were dismissed on the basis of decoupling experiments. Direct particle–shock wave interactions are therefore indicated as the primary mechanism of sonofragmentation of molecular crystals.read more
Citations
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Journal ArticleDOI
Mathematical modelling of the evolution of the particle size distribution during ultrasound-induced breakage of aspirin crystals
TL;DR: In this paper, a population balance model for describing the crystal breakage that results from ultrasound is presented. But the model is not suitable for the case of single-crystal applications.
Journal ArticleDOI
Breakage and Particle Size Redistribution in an Ultrasound‐Intensified Leaching Process
TL;DR: In this paper, the breakage and particle size redistributions in an ultrasound-intensified leaching process were explored experimentally and analyzed statistically, and it was found that particle size distributions (PSDs) of this atomic crystal silica may be changed to a certain extent by ultrasound, but the width of PSD cannot be altered under the conditions considered.
Journal ArticleDOI
Microwave-assisted sonochemical synthesis of Cu and Mn doped GSH–ZnS polypeptide quantum dots and their enhanced photoelectrochemical properties
TL;DR: A series of Cu and Mn doped glutathione (GSH) and ZnS polypeptide quantum dots (QDs) were successfully prepared by a facile one-pot microwave-assisted sonochemical synthesis approach as mentioned in this paper.
DissertationDOI
Expansions of supramolecular chemistry: nanocrystals, pharmaceutical cocrystals, imaging, and decorated olefins
TL;DR: Sander as discussed by the authors submitted a thesis submitted in partial fulfillment of the requirements for the Doctor of Philosophy degree in Chemistry in the Graduate College of The University of Iowa, which was submitted by John Roy George Sander.
Journal ArticleDOI
Half-Time Heat Map Reveals Ultrasonic Effects on Morphology and Kinetics of Amyloidogenic Aggregation Reaction.
Kichitaro Nakajima,Hajime Toda,Keiichi Yamaguchi,Masatomo So,Kensuke Ikenaka,Hideki Mochizuki,Yuji Goto,Hirotsugu Ogi +7 more
TL;DR: In this paper, the authors investigated the morphology and structure of resultant aggregates, kinetics of fibril formation, and seed detection sensitivity under ultrasonication using β2-microglobulin and compared these characteristics under shaking, which has been traditionally adopted in amyloid-fibril assays.
References
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Journal ArticleDOI
Applications of ultrasound to materials chemistry
TL;DR: The chemical effects of ultrasound derive primarily from acoustic cavitation, which results in an enormous concentration of energy from the conversion of the kinetic energy of the liquid motion into heating of the contents of the bubble as mentioned in this paper.
Journal ArticleDOI
Applications of Ultrasound to the Synthesis of Nanostructured Materials
Jin Ho Bang,Kenneth S. Suslick +1 more
TL;DR: The fundamental principles of both synthetic methods and recent development in the applications of ultrasound in nanostructured materials synthesis are summarized.
Journal ArticleDOI
Interparticle collisions driven by ultrasound
TL;DR: The effects of high-intensity ultrasound on solid-liquid slurries were examined and Turbulent flow and shock waves produced by acoustic cavitation were found to drive metal particles together at sufficiently high velocities to induce melting upon collision.
Journal ArticleDOI
Inside a Collapsing Bubble: Sonoluminescence and the Conditions During Cavitation
TL;DR: Application of spectrometric methods of pyrometry as well as tools of plasma diagnostics to relative line intensities, profiles, and peak positions have allowed the determination of intracavity temperatures and pressures.
Journal ArticleDOI
Ultrasound-assisted crystallization (sonocrystallization).
TL;DR: The results obtained so far make foreseeable that crystal size distribution, and even crystal shape, can be 'tailored' by appropriate selection of the sonication conditions.