Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy
Sibi Raj,Sartaj Khurana,Ramesh Choudhari,Kavindra Kumar Kesari,Mohammad Amjad Kamal,Neha Garg,Janne Ruokolainen,Bhudev C. Das,Dhruv Kumar +8 more
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TLDR
Details of the nano-based therapeutics and diagnostics strategies, and the potential use of nanomedicines in cancer drug delivery and cancer therapy are discussed.About:
This article is published in Seminars in Cancer Biology.The article was published on 2021-02-01 and is currently open access. It has received 149 citations till now. The article focuses on the topics: Nanocarriers & Targeted therapy.read more
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Nanomaterials for cancer therapy: current progress and perspectives.
TL;DR: Nanomaterials are materials in the nanorange 1-100nm which possess unique optical, magnetic, and electrical properties as discussed by the authors, and they have been modified for a wide range of cancer therapies to overcome toxicity and lack of specificity.
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Biodegradable Polymeric Nanoparticles for Drug Delivery to Solid Tumors.
Agnese Gagliardi,Elena Giuliano,Eeda Venkateswararao,Massimo Fresta,Stefania Bulotta,Vibhudutta Awasthi,Donato Cosco +6 more
TL;DR: In this paper, the use of polymeric nanoparticles as drug delivery systems of anticancer compounds, their physico-chemical properties and their ability to be efficiently localized in specific tumor tissues have been described.
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Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol
Pooria Nakhaei,Ria Margiana,Dmitry Bokov,Walid Kamal Abdelbasset,Walid Kamal Abdelbasset,Mohammad Amin Jadidi Kouhbanani,Rajender S. Varma,Faroogh Marofi,Mostafa Jarahian,Nasrin Beheshtkhoo +9 more
TL;DR: The role of cholesterol in the stability of liposomes is discussed in this paper, where the authors focus on cholesterol as a promising material for liposome stability and provide an explanation for the stability promotion.
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Aptamers in biomedicine: selection strategies and recent advances
Geanina Ștefan,Geanina Ștefan,Oana Hosu,Karolien De Wael,María Jesús Lobo-Castañón,Cecilia Cristea +5 more
TL;DR: This review accounts for the 30th celebration of the SELEX technology underlining the most important aptamers’ achievements in the biomedical field within mostly the past five years.
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Nanoparticles in Clinical Translation for Cancer Therapy
Deepa Mundekkad,William C. Cho +1 more
TL;DR: This review enumerates various types of nanoparticles that have entered clinical trials for cancer treatment and the obstacles in the journey of nanodrug from clinic to market.
References
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Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Xavier Michalet,Fabien Pinaud,Laurent A. Bentolila,James M. Tsay,Sören Doose,J. Jack Li,Gobalakrishnan Sundaresan,Anna M. Wu,Sanjiv S. Gambhir,Sanjiv S. Gambhir,Shimon Weiss +10 more
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A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs
Yasuhiro Matsumura,Hiroshi Maeda +1 more
TL;DR: It is speculated that the tumoritropic accumulation of smancs and other proteins resulted because of the hypervasculature, an enhanced permeability to even macromolecules, and little recovery through either blood vessels or lymphatic vessels in tumors of tumor-bearing mice.
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In vivo cancer targeting and imaging with semiconductor quantum dots
TL;DR: Sensitive and multicolor fluorescence imaging of cancer cells under in vivo conditions are achieved and a whole-body macro-illumination system with wavelength-resolved spectral imaging is integrated for efficient background removal and precise delineation of weak spectral signatures.
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Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells.
TL;DR: The intracellular uptake of different sized and shaped colloidal gold nanoparticles is investigated and it is shown that kinetics and saturation concentrations are highly dependent upon the physical dimensions of the nanoparticles.
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Cancer nanotechnology: opportunities and challenges.
TL;DR: Nanotechnology is a multidisciplinary field, which covers a vast and diverse array of devices derived from engineering, biology, physics and chemistry that can provide essential breakthroughs in the fight against cancer.