Journal ArticleDOI
Structure and mechanism in the enzymic activity of carboxypeptidase A and relations to chemical sequence
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This article is published in Accounts of Chemical Research.The article was published on 1970-03-01. It has received 126 citations till now. The article focuses on the topics: Carboxypeptidase A & Carboxypeptidase.read more
Citations
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Journal ArticleDOI
Dynamics of folded proteins
TL;DR: The dynamics of a folded globular protein have been studied by solving the equations of motion for the atoms with an empirical potential energy function and suggest that the protein interior is fluid-like in that the local atom motions have a diffusional character.
Journal ArticleDOI
Synthetic analogues relevant to the structure and function of zinc enzymes.
Journal ArticleDOI
Analog approaches to the structure of the transition state in enzyme reactions
Journal ArticleDOI
The internal dynamics of globular proteins.
Martin Karplus,J. A. McCammon +1 more
TL;DR: The Internal Dynamics of Globular Protein (IDGP) as mentioned in this paper is a well-known model for the internal dynamics of protein structures and its dynamics in the context of protein synthesis.
Book ChapterDOI
Carboxypeptidase A: a protein and an enzyme.
TL;DR: This chapter discusses the relationship of the three-dimensional structures of bovine carboxypeptidase A, and of its complexes with substrates and inhibitors, to the functional behavior of this enzyme.
References
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A Partial Determination by X-ray Methods, and its Correlation with Chemical Data
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The mode of action of the crystalline pancreatic proteolytic enzymes.
Hans Neurath,George W. Schwert +1 more
Journal ArticleDOI
On the Conformation of the Hen Egg-White Lysozyme Molecule
TL;DR: Crystals of hen egg-white lysozyme, grown at pH 4.7, are tetragonal with a = b = 79.1 Å, c = 37.9 Å and the structure has been determined by X-ray analysis by the method of multiple isomorphous replacement developed in the studies of haemoglobin and myoglobin.
Related Papers (5)
Metallocarboxypeptidases: stability constants and enzymatic characteristics.
Joseph E. Coleman,Bert L. Vallee +1 more