Journal ArticleDOI
Studies on antianaphylactic agents—III
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TLDR
By the application of the Vilsmeier-Haack reaction to various o-hydroxyacetophenone derivatives, 4-oxo-4H-1-benzopyran-3-carboxaldehydes were synthesized in one step as discussed by the authors.About:
This article is published in Tetrahedron.The article was published on 1974-01-01. It has received 175 citations till now. The article focuses on the topics: Fragmentation (mass spectrometry) & Mass spectrum.read more
Citations
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ACTION DES CYANOARYLIDENES ACTIVES SUR LES β -CETO- δ -CARBETHOXYPHOSPHONATES ET PHOSPHINEOXYDES: SYNTHESE DE 2-AMINO-6-(PHOSPHONOMETHYL)-4H-PYRANES
TL;DR: In this paper, the reaction of β-keto-δ-carbethoxyphosphonates and phosphineoxides with active cyanoarylidenes has been studied.
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Experimental and theoretical approach to exploit the corrosion inhibition activity of 3-formyl chromone derivatives on mild steel in 1 m H2SO4
TL;DR: In this paper, 3-Formyl chromone derivatives, viz. 5-methoxy-3FC (5-Me-3fc), 6-hydroxy-3LCF (6-OH-3lc), and 7-hydroxyl-3c, were studied for the inhibition of mild steel corrosion in 1 m H2SO4 at different temperatures and concentrations.
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Structure-based design and synthesis of novel dual-target inhibitors against cyanobacterial fructose-1,6-bisphosphate aldolase and fructose-1,6-bisphosphatase.
Ding Li,Ding Li,Xinya Han,Qidong Tu,Qidong Tu,Lingling Feng,Di Wu,Yao Sun,Haifeng Chen,Yongjian Li,Yanliang Ren,Jian Wan +11 more
TL;DR: A series of novel inhibitors were rationally designed, synthesized, and optimized based upon the structural and interactional information of both Cy-FBA-II and Cy- FBPase, and their inhibitory activities were examined in vitro and in vivo.
Journal ArticleDOI
Regioselective syntheses of 2- and 4-formylpyrido[2,1-b]benzoxazoles.
TL;DR: A mechanism for the formation of 5 involving sequential chlorination, dimerization, intramolecular elimination of HCl to form the oxazole ring, formylation twice, and regioselective intramolescular nucleophilic cyclization to construct the pyridone ring is proposed.
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Synthesis and evaluation of c-Src kinase inhibitory activity of pyridin-2(1H)-one derivatives
Karam Chand,Suchita Prasad,Rakesh Tiwari,Rakesh Tiwari,Amir Nasrolahi Shirazi,Amir Nasrolahi Shirazi,Sumit Kumar,Sumit Kumar,Keykavous Parang,Keykavous Parang,Sunil K. Sharma +10 more
TL;DR: In this perspective, a series of eighteen 2-pyridone derivatives were synthesized and evaluated for their c-Src kinase inhibitory activity, providing insights for further optimization of this scaffold for designing the next generation of 2-methoxybenzoyl derivatives as candidate SRC kinase inhibitors.
References
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3‐Acylchromone. XV. Mitt. über Untersuchungen an γ‐Pyronen
Fritz Eiden,H. Haverland +1 more
TL;DR: In 2-Stellung unsubstituierte 3-Acyl-chromone wurden aus 2-Hydroxy-ω-acyl-acetophenonen durch Reaktion with Orthoameisensaure-triathylester und Acetanhydrid oder aus 1-hydroxy-α-formylacetophenon and Acetanehydrid/Natriumacetat dargestellt as mentioned in this paper.
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Synthetic analogs of cortical hormones. i. homogentisic acid and ,2,5-trihydroxyacetophenone derivatives from 2,5-diacetoxy--diazoacetophenone
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The reactions of 2,2‐difluoro‐4‐methylnaphtho[l,2‐e]‐1,3,2‐dioxaborin and its [2,1‐e]isomer with N,N‐dimethylformamide
TL;DR: In this paper, the title compounds react with dimethylformamide in acetic anhydride to give dimethylamino-vinyl derivatives which, on treatment with base, yield benzochroman-4-ones.
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Pharmacological actions of baicalin and baicalein
TL;DR: In this paper, Baicalin and Baicalein, components of the drug, were investigated on active anaphylactic reaction in guinea pig, and the results obtained were compared with those of rutin, methylhesperidin and quercetin.