Journal ArticleDOI
Studies on kinetoplast DNA III. Kinetic complexity of kinetoplast and nuclear DNA from Leishmania tarentolae
Ronald D. Wesley,Larry Simpson +1 more
TLDR
Quantitative renaturation kinetic studies of purified kinetoplast minicircular DNA from Leishmania tarentolae indicated that there is probably one but certainly no more than two classes of identically sized minicircles in terms of DNA base sequences.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1973-09-07. It has received 36 citations till now. The article focuses on the topics: Kinetoplast & Minicircle.read more
Citations
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Book ChapterDOI
Kinetoplast DNA in trypanosomid flagellates.
TL;DR: This chapter discusses the kinetoplast DNA in trypanosomid flagellates and focuses on the general characteristics of minicircle DNA of several species, including Trypanosoma brucei, TrypanOSoma equiperdum, Leishmania tarentolae,Crithidia fasciculata, and Crithidia luciliae.
Journal ArticleDOI
Tandem arrangement of tubulin genes in the protozoan parasite Leishmania enriettii.
TL;DR: The arrangement of developmentally regulated alpha- and beta-tubulin genes has been studied in the parasitic protozoan Leishmania enriettii by using Southern blot hybridization analysis.
Journal ArticleDOI
Characterization of DNA from Trypanosoma brucei and related trypanosomes by restriction endonuclease digestion
TL;DR: By blotting the DNA on to nitrocellulose strips the restriction endonuclease recognition sites around genes available in cloned form can be analysed by molecular hybridization and this is demonstrated for the gene which codes for one of the variant surface glycoproteins of T. brucei.
Book ChapterDOI
Mitochondrial DNA of kinetoplastids.
Kenneth Stuart,Jean E. Feagin +1 more
TL;DR: This chapter highlights mitochondrial DNA of kinetoplastids, which comprises two classes of unrelated circular molecules, maxicircles and minicircle, and in each cell these molecules are catenated into a single massive network.
Journal ArticleDOI
Heterogeneity of the kinetoplast DNA molecules of Trypanosoma cruzi.
Guy Riou,Pierre Yot +1 more
TL;DR: Kinetoplast DNA (kDNA) of the culture form of Trypanosoma cruzi is cleaved by restriction endonucleases and the analysis of the cleavage patterns proves that the minicircles are heterogeneous in base sequences.
References
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Journal ArticleDOI
Repeated Sequences in DNA
Roy J. Britten,D. E. Kohne +1 more
TL;DR: Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms and used in medicine, science, and engineering.
Journal ArticleDOI
Kinetics of renaturation of DNA.
James G. Wetmur,Norman Davidson +1 more
TL;DR: It is proposed that the mechanism of the reaction involves the joining of short, homologous sites on the two strands followed by a fast, reversible zippering reaction with forward rate constant kt, which explains the temperature and the GC dependence.
Book ChapterDOI
The Kinetoplast of the Hernoflagellates
TL;DR: The existence of one mitochondrion per cell should be conclusively proved by the three-dimensional reconstruction technique and the replication of K-DNA should be investigated, both in terms of the intracellular regulatory mechanisms involved in the synchrony of the kinetoplast S period with the nuclear S period and the actual replication of the minicircles and long DNA molecules.
Book ChapterDOI
Mitochondrial DNA: physicochemical properties, replication, and genetic function.
Piet Borst,A.M. Kroon +1 more
TL;DR: The physicochemical properties, replication, and genetic function of mitochondrial DNA is discussed, and several aspects of mitochondrial biogenesis are discussed.
Journal ArticleDOI
Nutrition of a Hemoflagellate (Leishmania tarentolae) Having an Interchangeable Requirement for Choline or Pyridoxal.
TL;DR: The leptomonads of Leishmania tarentolae grew through nine transfers but they were mostly somewhat rounded and aflagellate and only slightly better growth occurred in a partially defined medium containing bovine plasma fraction V.
Related Papers (5)
Isolation and characterization of kinetoplast DNA from Leishmania tarentolae.
Larry Simpson,Agda da Silva +1 more