Journal ArticleDOI
Synthesis of 1,8-Dioxo-decahydroacridine Derivatives via Ru-Catalyzed Acceptorless Dehydrogenative Multicomponent Reaction.
Nandita Biswas,Dipankar Srimani +1 more
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TLDR
In this article, a Ru-catalyzed acceptorless dehydrogenative multicomponent reaction has been developed to synthesize biologically active 1,8-dioxodecahydroacridine derivatives.Abstract:
A Ru-catalyzed acceptorless dehydrogenative multicomponent reaction has been developed. This reaction offers a cost-effective and simple operational strategy to synthesize biologically active 1,8-dioxodecahydroacridine derivatives. The protocol provides a wide range of substrate scope and various functional groups are also well tolerated under the reaction condition. To shed light on the mechanistic and kinetic study, some controlled experiments and deuterium labeling experiments were executed. A time-dependent product distribution experiment is also presented and the reaction scale-up is performed to highlight the practical utility of this strategy.read more
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An Efficient Combinatorial Synthesis of Novel Thiazolidinone‐bis Schiff Base Hybrids Using One‐Pot Multicomponent Reaction
TL;DR: In this article , a facile multicomponent synthesis of novel thiazolidinone-bis Schiff base hybrids has been developed using readily available starting materials, such as isothiocyanate, hydrazine, aldehyde and α-bromoester.
References
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