Journal ArticleDOI
Synthetic polypeptides for biomedical applications
TLDR
This article summarizes recent developments in the synthesis of copolypeptides from polymerization of α-amino acid-N-carboxyanhydrides (NCAs), focusing on their development for potential use in biomedical applications.About:
This article is published in Progress in Polymer Science.The article was published on 2007-08-01. It has received 463 citations till now.read more
Citations
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Rethinking amide bond synthesis
TL;DR: A new generation of amide-forming reactions are reviewed and summarize their potential application to current synthetic challenges, including the development of catalytic amide formation, the synthesis of therapeutic peptides and the preparation of modified peptide and proteins.
Journal ArticleDOI
Biodegradable synthetic polymers: Preparation, functionalization and biomedical application
TL;DR: This review presents a comprehensive introduction to various types of synthetic biodegradable polymers with reactive groups and bioactive groups, and further describes their structure, preparation procedures and properties.
Journal ArticleDOI
Catechol-Based Biomimetic Functional Materials
TL;DR: It is shown that catechols can be found either as simple molecular systems, forming part of supramolacular structures, coordinated to different metal ions or as macromolecules mostly arising from polymerization mechanisms through covalent bonds.
Journal ArticleDOI
Catechols as versatile platforms in polymer chemistry
Emilie Faure,Céline Falentin-Daudré,Christine Jérôme,Joel Lyskawa,David Fournier,Patrice Woisel,Christophe Detrembleur +6 more
TL;DR: The aim of this paper is to review for the first time the main synthetic approaches developed for the design of novel catechol-based polymer materials and highlight the importance of these groups as versatile platforms for further functionalization of the macromolecular structures, but also surfaces.
Journal ArticleDOI
Catalytic amide formation from non-activated carboxylic acids and amines
TL;DR: A comprehensive overview of homogeneous and heterogeneous catalytic methods is presented, covering biocatalysts, Lewis acid catalysts based on boron and metals as well an assortment of other types of catalysts.
References
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Journal ArticleDOI
Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
TL;DR: Although modern synthetic biomaterials represent oversimplified mimics of natural ECMs lacking the essential natural temporal and spatial complexity, a growing symbiosis of materials engineering and cell biology may ultimately result in synthetic materials that contain the necessary signals to recapitulate developmental processes in tissue- and organ-specific differentiation and morphogenesis.
Book
Introduction to protein structure
Carl Ivar Branden,John Tooze +1 more
TL;DR: Part 1 BASIC STRUCTURAL PRINCIPLES: The Building Blocks and Motifs of Protein Structure and Part 2 STRUCTURE, FUNCTION and ENGINEERING: Structure, Function and Engineering.
Journal ArticleDOI
Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers
Gabriel A. Silva,Gabriel A. Silva,Catherine Czeisler,Krista L. Niece,Elia Beniash,Daniel A. Harrington,John A. Kessler,Samuel I. Stupp +7 more
TL;DR: The artificial nanofiber scaffold induced very rapid differentiation of cells into neurons, while discouraging the development of astrocytes, linked to the amplification of bioactive epitope presentation to cells by the nanofibers.
Journal ArticleDOI
Self-assembling organic nanotubes based on a cyclic peptide architecture
TL;DR: The design, synthesis and characterization of a new class of organic nanotubes based on rationally designed cyclic polypeptides are reported, which may have possible applications in inclusion chemistry, catalysis, molecular electronics and molecular separation technology.