Tandem repeats within the inverted terminal repetition of vaccinia virus DNA
R Wittek,Bernard Moss +1 more
TLDR
Tandem repeats within the inverted terminal repetition could serve to accelerate self-annealing of single strands of DNA to form circular structures during replication.About:
This article is published in Cell.The article was published on 1980-08-01 and is currently open access. It has received 126 citations till now. The article focuses on the topics: Restriction fragment & Tandem repeat.read more
Citations
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Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety
TL;DR: A genetically altered vaccinia virus that is unable to replicate in mammalian cells and produces diminished cytopathic effects retains the capacity for high-level gene expression and immunogenicity while promising exceptional safety for laboratory workers and potential vaccine recipients.
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Cloning yeast telomeres on linear plasmid vectors
TL;DR: The fact that yeast can recognize and use DNA ends from the distantly related organism Tetrahymena suggests that the structural features required for telomere replication and resolution have been highly conserved in evolution.
Journal ArticleDOI
Viruses and viruslike particles of eukaryotic algae.
TL;DR: In the next decade, this work envision the discovery of new algal viruses, clarification of their role in various ecosystems, discovery of commercially useful genes in these viruses, and exploitation of algal virus genetic elements in plant and algal biotechnology.
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Incompletely base-paired flip-flop terminal loops link the two DNA strands of the vaccinia virus genome into one uninterrupted polynucleotide chain
TL;DR: Self-priming and de novo start replication models, which involve a site-specific nick in one DNA strand proximal to the 104 nucleotide loop, account for the observed sequence inversions and incomplete base-pairing.
Journal ArticleDOI
Complete genome analysis of the mandarin fish infectious spleen and kidney necrosis iridovirus.
TL;DR: It is suggested that ISKNV, RSIV, sea bass iridovirus, grouper iridvirus, and African lampeye iridavirus may belong to a new genus of the Iridoviridae family and are tentatively referred to as cell hypertrophy iridOViruses.
References
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Incompletely base-paired flip-flop terminal loops link the two DNA strands of the vaccinia virus genome into one uninterrupted polynucleotide chain
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