Journal ArticleDOI
The awakening cortisol response: Methodological issues and significance
Reads0
Chats0
TLDR
A review explores reasons for discrepancies in normative data including confounding factors such as gender, age, awakening time, light and participant adherence that suggest the awakening cortisol response is under a distinct regulatory influence different from the rest of the diurnal cortisol secretory cycle.Abstract:
The awakening cortisol response (ACR) is a discrete and distinctive part of the cortisol circadian cycle. In healthy adults salivary free cortisol concentrations increase by between 50 and 160% in the first 30 min immediately post-awakening (approximate average increase of 9 nmol/l, range 4-15 nmol/l, estimated to be equivalent to about three secretory episodes). However there are no agreed norms for the absolute concentrations of free cortisol in saliva either immediately post-awakening (range of 4.7-18.5 nmol/l) or 30 min post-awakening (range of 8.6-21.9 nmol/l). This review explores reasons for these discrepancies in normative data including confounding factors such as gender, age, awakening time, light and participant adherence. Although the physiological role of the ACR has not been clearly defined evidence is discussed that suggests it is under a distinct regulatory influence, different from the rest of the diurnal cortisol secretory cycle. Despite the difficulties associated with its measurement a range of studies have demonstrated an association between the ACR and psychosocial variables, stress and health. However it remains unclear whether positive affect and good health are consistently associated with larger or smaller awakening responses. It is early days in the search for the role and significance of the ACR. Its putative role in the regulation of physiological function across the day (e.g. the immune system) and its sensitivity to psychosocial variables make it a prime candidate as an intermediary linking mind and health.read more
Citations
More filters
Journal ArticleDOI
Yoga for veterans with PTSD: Cognitive functioning, mental health, and salivary cortisol.
Belle Zaccari,Megan L. Callahan,Daniel Storzbach,Nancy McFarlane,Rebekah Hudson,Jennifer M. Loftis +5 more
TL;DR: Preliminary support for the practice of yoga to improve cognitive functioning (response inhibition) related to symptoms of PTSD while also improving mental health symptoms, sleep, and quality of life is provided.
Journal ArticleDOI
High cortisol awakening response in the aftermath of workplace violence exposure moderates the association between acute stress disorder symptoms and PTSD symptoms.
Marie-France Marin,Steve Geoffrion,Robert-Paul Juster,Charles-Édouard Giguère,Alain Marchand,Sonia J. Lupien,Stéphane Guay +6 more
TL;DR: The results suggest that higher cortisol awakening response is a protective factor in that it abolishes the relationship between acute stress disorder symptoms and subsequent PTSD symptoms.
Journal Article
Association of the Period3 clock gene length polymorphism with salivary cortisol secretion among police officers.
Michael D. Wirth,James B. Burch,James B. Burch,John M. Violanti,Cecil M. Burchfiel,Desta Fekedulegn,Michael E. Andrew,Hongmei Zhang,Diane B. Miller,Shawn D. Youngstedt,Shawn D. Youngstedt,James R. Hébert,John E. Vena +12 more
TL;DR: Cortisol secretion was modified among police officers with different PER3 VNTR clock gene variants.
Journal ArticleDOI
Alterations of postawakening cortisol parameters during a prolonged stress period Results of a prospective controlled study
Ulrike Weik,Renate Deinzer +1 more
TL;DR: The results of this prospective controlled study support notions that chronic stress induces increases of overall postawakening cortisol and indicate that the CAR is not affected by chronic stress and that the awakening concentration responds later than the AUC(G) to conditions of chronic stress as analyzed here.
Journal ArticleDOI
Modeling Cortisol Daily Rhythms of Family Caregivers of Individuals With Dementia: Daily Stressors and Adult Day Services Use
TL;DR: The findings suggested potential biophysiological benefits of daily ADS use for a sample that was under chronic stress and high levels of daily stress.
References
More filters
Journal ArticleDOI
Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change
TL;DR: It is shown that depending on which formula is used, different associations with other variables may emerge, and it is recommended to employ both formulas when analyzing data sets with repeated measures.
Journal ArticleDOI
Salivary cortisol in psychobiological research: an overview.
TL;DR: This overview intends to give a comprehensive introduction to the method of salivary cortisol assessment and to briefly discuss its application in different scientific disciplines.
Journal ArticleDOI
Free Cortisol Levels after Awakening: A Reliable Biological Marker for the Assessment of Adrenocortical Activity
Jens C. Pruessner,Oliver T. Wolf,Dirk H. Hellhammer,Angelika Buske-Kirschbaum,K. von Auer,Silke Jobst,F. Kaspers,Clemens Kirschbaum +7 more
TL;DR: Early morning cortisol levels can be a reliable biological marker for the individual's adrenocortical activity when measured repeatedly with strict reference to the time of awakening, in contrast to single assessments at fixed times.
Journal ArticleDOI
Diurnal Cortisol Rhythm as a Predictor of Breast Cancer Survival
TL;DR: Patients with metastatic breast cancer whose diurnal cortisol rhythms were flattened or abnormal had earlier mortality, and suppression of NK cell count and NK function may be a mediator or a marker of more rapid disease progression.
Journal ArticleDOI
Burnout, perceived stress, and cortisol responses to awakening.
TL;DR: Sixty-six teachers from local public schools (42 womenand 24 men, mean age 42 6 5 years) were asked to sample saliva for cortisol analysis on 3 consecutive days as discussed by the authors.