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Journal ArticleDOI

The cortisol awakening response (CAR): Facts and future directions

TLDR
It is hypothesized that the anticipation of the upcoming day is of major relevance for the magnitude of the cortisol awakening response, and considerations are addressed concerning the exact function of the CAR.
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This article is published in International Journal of Psychophysiology.The article was published on 2009-04-01. It has received 1069 citations till now. The article focuses on the topics: Cortisol awakening response & Cortisol secretion.

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Salivary cortisol as a biomarker in stress research.

TL;DR: The present paper addresses several psychological and biological variables, which may account for such dissociations, and aims to help researchers to rate the validity and psychobiological significance of salivary cortisol as an HPAA biomarker of stress in their experiments.
Journal ArticleDOI

Assessment of the cortisol awakening response: Expert consensus guidelines.

TL;DR: Consensus guidelines are presented on central aspects of CAR assessment, including objective control of sampling accuracy/adherence, participant instructions, covariate accounting, sampling protocols, quantification strategies as well as reporting and interpreting of CAR data.
Journal ArticleDOI

The Neuroendocrinology of Social Isolation

TL;DR: Investigation of neuroendocrine stress mechanisms that may be involved suggest that chronic social isolation increases the activation of the hypothalamic pituitary adrenocortical axis, and these effects are more dependent on the disruption of a social bond between a significant pair than objective isolation per se.
Journal ArticleDOI

The cortisol awakening response: more than a measure of HPA axis function.

TL;DR: Evidence is presented for reduced adrenal sensitivity to rising levels of ACTH in the pre-awakening period, mediated by an extra-pituitary pathway to the adrenal from the suprachiasmatic nucleus (SCN).
Journal ArticleDOI

Psychobiological Mechanisms Underlying the Social Buffering of the Hypothalamic-Pituitary-Adrenocortical Axis: A Review of Animal Models and Human Studies Across Development

TL;DR: A working conceptual model is provided focused on the role of oxytocinergic systems and prefrontal neural networks as 2 of the putative biological mediators of this process, and it is proposed that therole of early experiences is critical in shaping later social buffering effects.
References
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Book

The Hippocampus as a Cognitive Map

John O'Keefe, +1 more
TL;DR: The amnesic syndrome is presented as an extension of the theory to humans and the role of operators in the locale system is examined.
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The hippocampus as a cognitive map

R.E. Passingham
- 01 Jun 1979 - 
TL;DR: Introduction to cognitive PDF heidegger and cognitive science PDF group cognitive therapy Group cognitive therapy for addictions handbook of brief cognitive behavioral therapy gurwitschs relevancy for cognitive science, and imagery creativity and discovery a cognitive perspective.
Journal ArticleDOI

The Concepts of Stress and Stress System Disorders: Overview of Physical and Behavioral Homeostasis

TL;DR: The main components of the stress system are the corticotropin-releasing hormone and locus ceruleus-norepinephrine/autonomic systems and their peripheral effectors, the pituitary-adrenal axis, and the limbs of the autonomic system as discussed by the authors.
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Stress and the Individual: Mechanisms Leading to Disease

TL;DR: A new formulation of the relationship between stress and the processes leading to disease is presented, emphasizing the cascading relationships between environmental factors and genetic predispositions that lead to large individual differences in susceptibility to stress and, in some cases, to disease.
Journal ArticleDOI

Brain corticosteroid receptor balance in health and disease.

TL;DR: The balance in actions mediated by the two corticosteroid receptor types in these neurons appears critical for neuronal excitability, stress responsiveness, and behavioral adaptation and Dysregulation of this MR/GR balance brings neurons in a vulnerable state with consequences for regulation of the stress response and enhanced vulnerability to disease in genetically predisposed individuals.
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