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The clinical spectrum of IgG4-related disease

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TLDR
Presenting features of IgG4-RD vary substantially according to the specialty to which patients present first; in addition, the disease can be diagnosed unexpectedly in pathological specimens or identified incidentally on radiology studies.
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IgG4-related disease

TL;DR: Identification of specific antigens and T-cell clones that drive the disease will be the first steps to elucidate the pathogenesis of IgG4-related disease.
Journal ArticleDOI

Diagnostic Approach to the Complexity of IgG4-Related Disease.

TL;DR: Most recent knowledge about the clinical, laboratory, radiological, and pathological characteristics of IgG4-RD that may guide the physician to establish an early diagnosis are provided.
Journal ArticleDOI

Therapeutic approach to IgG4-related disease: A systematic review.

TL;DR: Wide heterogeneity was observed with respect to the first-line therapeutic approaches used for the different organ-specific disease subsets, including significant differences in the mean dose of glucocorticoids used.
References
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Journal ArticleDOI

High serum IgG4 concentrations in patients with sclerosing pancreatitis.

TL;DR: Patients with sclerosing pancreatitis have high serum IgG4 concentrations, providing a useful means of distinguishing this disorder from other diseases of the pancreas or biliary tract.
Journal ArticleDOI

Consensus statement on the pathology of IgG4-related disease

TL;DR: This statement proposes a terminology scheme for the diagnosis of IgG4-related disease that is based primarily on the morphological appearance on biopsy, and advocates the use of strict criteria for accepting newly proposed entities or sites as components of the IgG 4- related disease spectrum.
Journal ArticleDOI

A new clinicopathological entity of IgG4-related autoimmune disease

TL;DR: It is suggested that AIP is not simply pancreatitis but that it is a pancreatic lesion involved in IgG4-related systemic disease with extensive organ involvement, and a new clinicopathological entity is proposed.
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