Journal ArticleDOI
The effects of ACTH, adrenalectomy and dexamethasone on the acquisition of an avoidance response in rats.
TLDR
The action of ACTH on avoidance conditioning is clearly extra-adrenal, but ACTH is not essential to normal performance, at least when high levels of glucocorticoids are present.About:
This article is published in Physiology & Behavior.The article was published on 1970-08-01. It has received 75 citations till now. The article focuses on the topics: ACTH inhibitor & Avoidance response.read more
Citations
More filters
Journal ArticleDOI
Increased acquisition of a complex appetitive task after MSH and MIF.
Lois O. Stratton,Lois O. Stratton,Lois O. Stratton,Abba J. Kastin,Abba J. Kastin,Abba J. Kastin +5 more
TL;DR: The results demonstrated that both MSH and MIF-I could facilitate the acquisition of an appetitive task which seemed of sufficient complexity to emphasize differences in performance.
Journal ArticleDOI
Learning and memory processes of an ACTH4–9 analog (ebiratide; Hoe 427) in mice and rats
TL;DR: Ebiratide was most effective in a dose range of 1-10 micrograms/kg SC and with all five training and testing procedures.
Journal ArticleDOI
Acth4−10 and improved use of information in rats
TL;DR: Water-deprived rats were trained to approach one of four tables in an elevated X-maze for water reward and the percentage of correct responses on the first trial was greater after 75 µg of ACTH4−10.
Journal ArticleDOI
Effects of an ACTH/MSH(4–9) analog (HOE 427) on the sleep EEG and nocturnal hormonal secretion in humans
TL;DR: The synthetic ACTH/MSH(4-9) analog HOE 427 ("ebiratide") was administered intravenously in a pulsatile mode 4 times to study its effect on the sleep EEG and on concomitant hormonal secretion of cortisol and growth hormone, suggesting that peripherally administered neuropeptides have specific nonendocrine behavioral effects.
References
More filters
Journal ArticleDOI
Some Studies of the Protein-Binding of Steroids and Their Application to the Routine Micro and Ultramicro Measurement of Various Steroids in Body Fluids by Competitive Protein-Binding Radioassay
TL;DR: A 100-fold increase in sensitivity has now been achieved by using tritiated steroids in place of 14C-labeled steroids, by utilizing the CBG's of species other than man, and by using adsorption in Place of dialysis or gel filtration.
Journal ArticleDOI
Fluorometric Determination of Corticosterone and Cortisol in 0.02–0.05 Milliliters of Plasma or Submilligram Samples of Adrenal Tissue1
Journal ArticleDOI
Long Term and Short Term Effects on Retention of a Conditioned Avoidance Response in Rats by Treatment with Long Acting Pitressin and α-MSH
D. de Wied,B. Bohus +1 more
TL;DR: It is found that the rapid extinction of a CAR which occurs after posterior lobectomy or hypophysectomy can be prevented by treatment with ACTH, melanocyte stimulating hormone (α-MSH) or lysine vasopressin given during the extinction period.
Journal ArticleDOI
Inhibitory Effect of ACTH and Related Peptides on Extinction of Conditioned Avoidance Behavior in Rats
TL;DR: ACTH, administered during extinction, delays extinction of an avoidance response in rats and results were interpreted to indicate that the active part of ACTH in this respect is located in the N-terminal part of the molecule, presumably in the first 10 amino acids.
Journal ArticleDOI
Influence of anterior pituitary on avoidance learning and escape behavior.
TL;DR: Adenohypophysectomized rats were subjected to an avoidance learning procedure and only 6 of 21 rats achieved the conditioning criterion against 14 of 18 sham-operated controls.
Related Papers (5)
Inhibitory Effect of ACTH and Related Peptides on Extinction of Conditioned Avoidance Behavior in Rats
The effect of adrenocorticotrophic hormone (ACTH) on avoidance conditioning in the rat.
Murphy Jv,Miller Re +1 more