The effects of surgery on tumor growth: a century of investigations
TLDR
The idea that surgical cancer resection has both beneficial and adverse effects upon cancer spread and growth that result from the modulation of tumor dormancy by the resection should be considered a potentially fruitful working hypothesis.About:
This article is published in Annals of Oncology.The article was published on 2008-11-01 and is currently open access. It has received 338 citations till now. The article focuses on the topics: Metastasis & Cancer.read more
Citations
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Hallmarks of cancer: the next generation.
TL;DR: Recognition of the widespread applicability of these concepts will increasingly affect the development of new means to treat human cancer.
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Microenvironmental regulation of therapeutic response in cancer.
Florian Klemm,Johanna A. Joyce +1 more
TL;DR: This review examines recent advances in understanding of the contribution of the TME during cancer therapy and discusses key concepts that may be amenable to therapeutic intervention.
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Guidelines on the radical management of patients with lung cancer
Eric Lim,David R Baldwin,M. Beckles,John P. Duffy,James Entwisle,Corinne Faivre-Finn,Keith M. Kerr,Alistair Macfie,Jim McGuigan,Simon P. G. Padley,Sanjay Popat,Nicholas Screaton,Michael Snee,David A. Waller,Chris Warburton,Thida Win +15 more
TL;DR: A joint initiative by the British Thoracic Society and the Society for Cardiothoracic Surgery was undertaken to update the 2001 guidelines for the selection and assessment of patients with lung cancer who can potentially be managed by radical treatment.
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Surgery for Cancer: A Trigger for Metastases
TL;DR: The role of perioperative factors, including anesthesia, transfusions, hypothermia, and postoperative complications, as probable deleterious factors contributing to early recurrence are addressed.
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In situ activation of platelets with checkpoint inhibitors for post-surgical cancer immunotherapy
TL;DR: It is shown that conjugating anti-PDL1 (engineered monoclonal antibodies against programmed-death ligand 1) to the surface of platelets can reduce post-surgical tumour recurrence and metastasis, and that the administration of platelet-bound anti- PDL1 significantly prolonged overall mouse survival after surgery.
References
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Angiogenesis in cancer, vascular, rheumatoid and other disease
TL;DR: Think of the switch to the angiogenic phenotype as a net balance of positive and negative regulators of blood vessel growth, which may dictate whether a primary tumour grows rapidly or slowly and whether metastases grow at all.
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Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma
Michael S. O'Reilly,Michael S. O'Reilly,Lars Holmgren,Lars Holmgren,Yuen Shing,Yuen Shing,Catherine Chen,Catherine Chen,Rosalind A. Rosenthal,Rosalind A. Rosenthal,Marsha A. Moses,Marsha A. Moses,William S. Lane,Yihai Cao,E. Helene Sage,Judah Folkman +15 more
TL;DR: It is shown that the inhibition of metastases by a primary mouse tumor is mediated, at least in part, by angiostatin, and a corresponding fragment of human plasminogen has similar activity.
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Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial
Antonio M. Lacy,Juan Carlos García-Valdecasas,Salvadora Delgado,Antoni Castells,Pilar Taura,Josep M. Piqué,Josep Visa +6 more
TL;DR: LAC is more effective than OC for treatment of colon cancer in terms of morbidity, hospital stay, tumour recurrence, and cancer-related survival.