Journal ArticleDOI
The impact of oral anticoagulation on time to surgery in patients hospitalized with hip fracture.
Thomas Tran,Aurélien Delluc,Carine de Wit,William Petrcich,Grégoire Le Gal,Grégoire Le Gal,Marc Carrier,Marc Carrier +7 more
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TLDR
A case control study comparing TTS in consecutively admitted hip fracture patients receiving either a DOAC or VKA with age- and gender-matched controls between January 1, 2010 and March 24, 2014 to determine how anticoagulation with a VKA or DOAC affects TTS.About:
This article is published in Thrombosis Research.The article was published on 2015-11-01. It has received 77 citations till now. The article focuses on the topics: Hip fracture.read more
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Journal ArticleDOI
Do Patients Taking Warfarin Experience Delays to Theatre, Longer Hospital Stay, and Poorer Survival After Hip Fracture?
TL;DR: After controlling for multiple prognostic factors such as age, sex, ASA score, AMTS, fracture type, operation type, and WAI, warfarin therapy at the time of injury is associated with increased time to surgery, length of stay, and decreased survival.
Journal ArticleDOI
Impact of Direct Oral Anticoagulants in Patients With Hip Fractures
Martin Bruckbauer,Oliver Prexl,Wolfgang G. Voelckel,Bernhard Ziegler,Oliver Grottke,Marc Maegele,Herbert Schöchl +6 more
TL;DR: The authors found no evidence of higher bleeding rates in HF patients on DOACs compared with COUs, and suggested earlier HF fixation might be indicated in DOAC patients.
Journal ArticleDOI
Morbidity and mortality after fragility hip fracture surgery in patients receiving vitamin K antagonists and direct oral anticoagulants.
Tal Frenkel Rutenberg,Steven Velkes,Steven Velkes,Maria Vitenberg,Avi Leader,Avi Leader,Yael Halavy,Pia Raanani,Pia Raanani,Mustafa Yassin,Mustafa Yassin,Galia Spectre,Galia Spectre +12 more
TL;DR: While preoperative anticoagulation delays surgery following fragility hip fractures, this delay was not found to be related to increased morbidity or mortality.
Journal ArticleDOI
Hip Fractures: Therapy, Timing, and Complication Spectrum.
TL;DR: Investigation of the treatment of Femur fractures and the type of femur fracture‐associated complications regarding timing of surgery and length of hospital stay finds no consistency in the results.
Journal ArticleDOI
Impact of oral anticoagulation on proximal femur fractures treated within 24 h - A retrospective chart review.
TL;DR: Early surgical care of proximal femur fractures is safe even in patients with anticoagulant medication, and patients on DOAC should be preoperatively prepared for possibly intraoperative transfusion.
References
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Journal ArticleDOI
Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients: Definitions of major bleeding in clinical studies
S. Schulman,C. Kearon +1 more
TL;DR: A definition of major bleeding in non‐surgical patients was developed that should be applicable to studies with all agents that interfere with hemostasis, including anticoagulants, platelet function inhibitors and fibrinolytic drugs.
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Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients.
Sam Schulman,U. Angerås,David Bergqvist,Bengt I. Eriksson,Michael R. Lassen,William D. Fisher +5 more
TL;DR: A definition of major bleeding that should be applicable to all agents that interfere with hemostasis is developed and is to seek approval from the regulatory authorities to enhance its incorporation into future clinical trial protocols.
Journal ArticleDOI
Incidence and mortality of hip fractures in the United States.
TL;DR: In the United States, hip fracture rates and subsequent mortality among persons 65 years and older are declining, and comorbidities among patients with hip fractures have increased.
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Periprocedural Bleeding and Thromboembolic Events With Dabigatran Compared With Warfarin Results From the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Randomized Trial
Jeff S. Healey,John W. Eikelboom,James D. Douketis,Lars Wallentin,Jonas Oldgren,Sean Yang,Ellison Themeles,Hein Heidbuchel,Alvaro Avezum,Paul A. Reilly,Stuart J. Connolly,Salim Yusuf,Michael D. Ezekowitz +12 more
TL;DR: In this article, the periprocedural bleeding risk of patients in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial treated with dabigatran and warfarin was compared.
Journal ArticleDOI
Time trends and demography of mortality after fractured neck of femur in an English population, 1968-98: database study.
TL;DR: The high mortality rates, and the fact that they have not fallen over the past 20 years, reinforce the need for measures to prevent osteoporosis and falls and their consequences in elderly people.