Journal ArticleDOI
The posterior dominant rhythm: an electroencephalographic biomarker for cognitive recovery after general anaesthesia.
Alyssa K. Labonte,Mohammadmehdi Kafashan,Emma R. Huels,Stefanie Blain-Moraes,Mathias Basner,Max B. Kelz,George A. Mashour,Michael S. Avidan,Ben J.A. Palanca,Maxwell R. Muench,Vijay Tarnal,Giancarlo Vanini,E. Andrew Ochroch,Rosemary M G Hogg,Marlon Schwarz,Ellen Janke,Goodarz Golmirzaie,Paul Picton,Andrew R. McKinstry-Wu +18 more
TLDR
The posterior dominant rhythm (PDR) was the first oscillatory pattern noted in the EEG and has been investigated for tracking cognitive dysfunction after anaesthetic-induced loss of consciousness as mentioned in this paper .Abstract:
The posterior dominant rhythm (PDR) was the first oscillatory pattern noted in the EEG. Evoked by wakeful eyelid closure, these oscillations dissipate over seconds during loss of arousal. The peak frequency of the PDR maintains stability over years, suggesting utility as a state biomarker in the surveillance of acute cognitive impairments. This EEG signature has not been systematically investigated for tracking cognitive dysfunction after anaesthetic-induced loss of consciousness.This substudy of Reconstructing Consciousness and Cognition (NCT01911195) investigated the PDR and cognitive function in 60 adult volunteers randomised to either 3 h of isoflurane general anaesthesia or resting wakefulness. Serial measurements of EEG power and cognitive task performance were assessed relative to pre-intervention baseline. Mixed-effects models allowed quantification of PDR and neurocognitive trajectories after return of responsiveness (ROR).Individuals in the control group showed stability in the PDR peak frequency over several hours (median difference/inter-quartile range [IQR] of 0.02/0.20 Hz, P=0.39). After isoflurane general anaesthesia, the PDR peak frequency was initially reduced at ROR (median difference/IQR of 0.88/0.65 Hz, P<0.001). PDR peak frequency recovered at a rate of 0.20 Hz h-1. After ROR, the PDR peak frequency correlated with reaction time and accuracy on multiple cognitive tasks (P<0.001).The temporal trajectory of the PDR peak frequency could be a useful perioperative marker for tracking cognitive dysfunction on the order of hours after surgery, particularly for cognitive domains of working memory, visuomotor speed, and executive function.NCT01911195. read more
Citations
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Journal ArticleDOI
Oscillatory and aperiodic neuronal activity in working memory following anesthesia
J. Lendner,Ulrich Harler,Jonathan Daume,Andreas K. Engel,Christian Zöllner,Till R. Schneider,Marlene Fischer +6 more
TL;DR: In this article , the brain activity in men undergoing prostatectomy under general anesthesia was measured by EEG and showed a dissociation between match and mismatch accuracy (match*session F1,25 = 3.866, p = 0.902, d = −0.060).
Journal ArticleDOI
Disrupted relationship between intrinsic neural timescales and alpha peak frequency during unconscious states – A high-density EEG study
Andrea Buccellato,Di Zang,Federico Zilio,Javier Gomez-Pilar,Zhe Wang,Zengxin Qi,Ruizhe Zheng,Ze-Yu Xu,Xuehai Wu,Patrizia Bisiacchi,Alessandra Del Felice,Ying Mao,Georg Northoff +12 more
TL;DR: In this article , the authors measured the brain's capacity for input processing on shorter (APF) and longer (autocorrelation window, ACW) timescales on resting state high-density EEG (256 channels) recordings and compared them across different consciousness levels (awake/conscious, ketamine and sevoflurane anaesthesia, unresponsive wakefulness, minimally conscious state).
Journal ArticleDOI
Electroencephalogram Features of Perioperative Neurocognitive Disorders in Elderly Patients: A Narrative Review of the Clinical Literature
TL;DR: A review of the application of multi-channel EEG monitoring to predict the incidence of PND in older patients confirmed that the abnormal variation in EEG power and functional connectivity between distant brain regions was closely related to the incidence and long-term poor outcomes of P ND in older adults.
Journal ArticleDOI
A Pilot Investigation Evaluating Relative Changes in Fronto-Occipital Alpha and Beta Spectral Power as Measurement of Anesthesia Hypnotic Depth
Jong Seog Ahn,Melih Burak ÖZDEMİR>,Richard Raatzsch,Anil K. Rustgi,Antonio Bernad,Fella Lahmar +5 more
TL;DR: In this article , the reduced power alpha beta (RPAB) index was used to measure the ratio of alpha and beta activity in the anterior-posterior axis of the brain.
Posted ContentDOI
Changes of oscillatory and aperiodic neuronal activity in working memory following anaesthesia: a prospective observational study
J. Lendner,Ulrich Harler,Jonathan Daume,Andreas K. Engel,Christian Zöllner,Till R. Schneider,Marlene Fischer +6 more
TL;DR: Aperiodic activity provides a novel electrophysiological biomarker to identify patients at risk for developing perioperative neurocognitive decline in male patients scheduled for elective radical prostatectomy under general anaesthesia.
References
More filters
Journal ArticleDOI
EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis
TL;DR: In this article, it is suggested to adjust the frequency windows of alpha and theta for each subject by using individual alpha frequency as an anchor point, based on this procedure, a consistent interpretation of a variety of findings is made possible.
Journal ArticleDOI
α-Band Electroencephalographic Activity over Occipital Cortex Indexes Visuospatial Attention Bias and Predicts Visual Target Detection
TL;DR: Electroencephalography data indicate that collateral modulations of posterior α-activity, the momentary bias of visuospatial attention, and imminent visual processing are linked, and suggest that the Momentary direction of attention, predicting spatial biases in imminent visualprocessing, can be estimated from a lateralization index of posterior β-activity.
Journal ArticleDOI
The berger rhythm: potential changes from the occipital lobes in man
E. D. Adrian,B. H. C. Matthews +1 more
Journal ArticleDOI
Electroencephalogram signatures of loss and recovery of consciousness from propofol
Patrick L. Purdon,Eric T. Pierce,Eran A. Mukamel,Eran A. Mukamel,Michael J. Prerau,John L. Walsh,Kin Foon Kevin Wong,Andres F. Salazar-Gomez,Priscilla G. Harrell,Aaron L. Sampson,Aylin Cimenser,ShiNung Ching,Nancy Kopell,Casie Tavares-Stoeckel,Kathleen Habeeb,Rebecca C. Merhar,Emery N. Brown +16 more
TL;DR: This work found specific behavioral and electrophysiological changes that mark the transition between consciousness and unconsciousness induced by propofol, one of the most commonly used anesthetic drugs.
Journal ArticleDOI
Über das Elektrenkephalogramm des Menschen: Fünfte Mitteilung
TL;DR: In this paper, the Aufnahmen des Elektrenkephalogramms (E.E.G.) with dem Oscillographen berichtet are discussed.
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