Journal ArticleDOI
The Potential of Flavonoids and Tannins from Medicinal Plants as Anticancer Agents.
Reads0
Chats0
TLDR
The cytostatic/antitumor effect of the individual compounds extracted from plants and/or of the plants polyphenolic extracts are considered, in order to point out the most significant constituents or plants with anticancer potential.Abstract:
The tendency of using herbs extracts or natural compounds extracted from herbs for preventing or treating different illnesses, including cancer, continues to be an alternative to drug use. Many studies of plant compounds aimed at finding substances with selective cytotoxicity on abnormal cells. Phenolic compounds, as important secondary metabolites from plants, are one of them. In this review, the recent literature data from the past five years about anticancer/antitumor effect of flavonoids and tannins extracted from medicinal plants are surveyed. The cytostatic/antitumor effects of the individual compounds extracted from plants and/or of the plants' polyphenolic extracts are considered, in order to point out the most significant constituents or plants with anticancer potential. The most important results concerning these compounds and their derivatives in cancer prevention and treatment, the importance of their chemical structure, their mechanism of action in vitro and in vivo, and some bioavailability aspects are discussed.read more
Citations
More filters
Journal ArticleDOI
Natural Compounds for Wood Protection against Fungi-A Review.
TL;DR: The collaboration with other industries interested in the utilisation of natural active compounds will reduce the associated costs, thus, will facilitate the successful implementation of alternative antifungal agents.
Journal ArticleDOI
Pathological and Pharmacological Roles of Mitochondrial Reactive Oxygen Species in Malignant Neoplasms: Therapies Involving Chemical Compounds, Natural Products, and Photosensitizers.
Yasuyoshi Miyata,Yuta Mukae,Junki Harada,Tsuyoshi Matsuda,Kensuke Mitsunari,Tomohiro Matsuo,Kojiro Ohba,Hideki Sakai +7 more
TL;DR: The association of mROS-related signaling in the molecular mechanisms of chemically synthesized and natural chemotherapeutic agents and photodynamic therapy is shown and is shown to be related to malignant neoplasms.
Journal ArticleDOI
Mulberry leaf polysaccharide extracted by response surface methodolog suppresses the proliferation, invasion and migration of MCF-7 breast cancer cells
Fan Feng,Ping Hu,Xingkui Tao +2 more
TL;DR: In this article , a low-temperature ultrasonic assisted method was used to extract mulberry leaf polysaccharide, and through employing the Design-Expert software, the optimal conditions for MLP extraction were ultrasonic power 179.34 W, ultrasonic time 13.92 min, and ratio (v/w, mL/g) of water to raw material 23.55.
Journal ArticleDOI
Australian native fruits and vegetables: Chemical composition, nutritional profile, bioactivity and potential valorization by industries.
Indeewarie Hemamali Dissanayake,Valeria Zak,Kirandeep Kaur,Kayla Jaye,Zahra Ayati,Dennis Hsu-Tung Chang,Chun Guang Li,Deep Jyoti Bhuyan +7 more
TL;DR: The potential of Australian native fruits and vegetables as functional food ingredients and in the prevention and treatment of different diseases is discussed in this paper , where a comprehensive summary and critical assessment of the studies performed in the last few decades to understand the phytochemical and nutritional profiles and therapeutic properties of Australia native vegetables is presented.
Journal ArticleDOI
Genistin modulates high-mobility group box protein 1 (HMGB1) and nuclear factor kappa-B (NF-κB) in Ehrlich-ascites-carcinoma-bearing mice
TL;DR: Genistin was evaluated for in vitro antiproliferative activity against breast cancer cell line (MCF-7 and MDA-MB-231) and exhibited good cytotoxic activities against both cell lines, suggesting an anti-inflammatory and anti-apoptotic activity.
References
More filters
Journal ArticleDOI
BCL-2 family members and the mitochondria in apoptosis
TL;DR: As the BCL-2 family members reside upstream of irreversible cellular damage and focus much of their efforts at the level of mitochondria, they play a pivotal role in deciding whether a cell will live or die, and it is argued that the amphipathic a-helical BH3 domain serves as a critical death domain in the pro-apoptotic members.
Journal ArticleDOI
Beneficial effects of green tea: A literature review
TL;DR: Long-term consumption of tea catechins could be beneficial against high-fat diet-induced obesity and type II diabetes and could reduce the risk of coronary disease.
Journal ArticleDOI
Notch signalling in solid tumours: a little bit of everything but not all the time
TL;DR: The discovery of Notch in Drosophila melanogaster opened the door to an ever-widening understanding of cellular processes that are controlled or influenced by Notch signalling, and a role for Notch is well established in haematological malignancies.
Journal ArticleDOI
Epigallocatechin-3-gallate (EGCG): chemical and biomedical perspectives.
TL;DR: This review highlights results from what the authors believe to be some of the most clinically significant recent studies and describes current developments in the stereoselective total synthesis of EGCG.
Journal ArticleDOI
Luteolin, a flavonoid, as an anticancer agent: A review.
Muhammad Imran,Abdur Rauf,Tareq Abu-Izneid,Muhammad Nadeem,Mohammad Ali Shariati,Imtiaz Ali Khan,Ali Imran,Ilkay Erdogan Orhan,Muhammad Rizwan,Muhammad Atif,Tanweer Aslam Gondal,Mohammad S. Mubarak +11 more
TL;DR: The present review article summarizes the progress of recent research on luteolin against several human cancers.