The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers.
Brendon M. Baker,Albert O. Gee,Robert B. Metter,Ashwin S. Nathan,Ross A. Marklein,Jason A. Burdick,Robert L. Mauck +6 more
TLDR
It is indicated that cell infiltration can be expedited in dense fibrous assemblies with the removal of sacrificial fibers, and this strategy may enhance in vitro and in vivo formation and maturation of functional constructs for fibrous tissue engineering.About:
This article is published in Biomaterials.The article was published on 2008-05-01 and is currently open access. It has received 613 citations till now.read more
Citations
More filters
Journal ArticleDOI
Design, fabrication and characterization of PCL electrospun scaffolds—a review
Amaia Cipitria,Amaia Cipitria,Anthony D. Skelton,Tim R. Dargaville,Paul D. Dalton,Paul D. Dalton,Dietmar W. Hutmacher,Dietmar W. Hutmacher +7 more
TL;DR: In this paper, a review summarizes literature on poly(3-caprolactone) and selected blends, and provides extensive descriptions of the broad range of parameters used in manufacturing such electrospun fibers.
Journal ArticleDOI
Recent advances in the development of GTR/GBR membranes for periodontal regeneration--a materials perspective.
Marco C. Bottino,Vinoy Thomas,Gudrun Schmidt,Yogesh K. Vohra,Tien-Min G. Chu,Michael J. Kowolik,Gregg M. Janowski +6 more
TL;DR: It is hypothesized that the next-generation of guided tissue and guided bone regeneration (GTR/GBR) membranes for periodontal tissue engineering will be a biologically active, spatially designed and functionally graded nanofibrous biomaterial that closely mimics the native extra-cellular matrix (ECM).
Journal ArticleDOI
Scaffold: A Novel Carrier for Cell and Drug Delivery
TL;DR: The present review gives a detailed account of the need for the development of scaffolds along with the materials used and techniques adopted to manufacture scaffolds for tissue engineering and for prolonged drug delivery.
Journal ArticleDOI
Electrospun nanofibers for regenerative medicine.
TL;DR: This Progress Report reviews recent progress in applying electrospun nanofibers to the emerging field of regenerative medicine and highlights applications of the nanofiber‐based scaffolds in four areas of regeneratives medicine that involve nerves, dural tissues, tendons, and the tendon‐to‐bone insertion site.
Journal ArticleDOI
Green composites: A review of material attributes and complementary applications
Michael P. M. Dicker,Michael P. M. Dicker,Peter F. Duckworth,Anna B. Baker,Guillaume Francois,Guillaume Francois,Mark K. Hazzard,Mark K. Hazzard,Paul M. Weaver +8 more
TL;DR: In this article, the authors provide guidelines for engineers and designers on the appropriate application of green composites and provide a concise summary of the major material attributes of green composite materials accompanied by graphical comparisons of their relative properties.
References
More filters
Journal ArticleDOI
Mesenchymal stem cells
TL;DR: The study of mesenchymal stem cells, whether isolated from embryos or adults, provides the basis for the emergence of a new therapeutic technology of self‐cell repair.
Journal ArticleDOI
Mesenchymal Stem Cells
TL;DR: The bone marrow contains multipotent MSC, which can be easily isolated and cultured in vitro, and the possibility of their clinical use in cell and gene therapy is analyzed.
Journal ArticleDOI
Nanometre diameter fibres of polymer, produced by electrospinning
Darrell H. Reneker,Iksoo Chun +1 more
TL;DR: More than 20 polymers, including polyethylene oxide, nylon, polyimide, DNA, polyaramid, and polyaniline, have been electrospun in this paper.
Journal ArticleDOI
The effect of processing variables on the morphology of electrospun nanofibers and textiles
TL;DR: In this paper, the effects of two of the most important processing parameters, spinning voltage and solution concentration, on the morphology of the fibers formed were evaluated systematically, and it was found that spinning voltage is strongly correlated with the formation of bead defects in the fibers, and that current measurements may be used to signal the onset of the processing voltage at which the bead defect density increases substantially.
Journal ArticleDOI
In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells
TL;DR: A culture system that facilitates the chondrogenic differentiation of rabbit bone marrow-derived mesenchymal progenitor cells has been developed in this article, where cells obtained in bone marrow aspirates were first isolated by monolayer culture and then transferred into tubes and allowed to form three-dimensional aggregates in a chemically defined medium.